Transgelin Antibodies

AND TAGLN ELISA kits, Transgelin Proteins

Many biological assays use antibodies to detect Transgelin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Transgelin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Transgelin antibodies...

We validate the specificity of these antibodies to Transgelin by testing them on tissues known to express TAGLN positively and negatively. Browse below to find the TAGLN antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TAGLN Infographic by Boster Bio

All TAGLN Products

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Product

Figures

Specificity

Applications

Price

Anti-Transgelin TAGLN Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A03962
100ul

Anti-TAGLN/Transgelin Antibody Picoband®

1 Citations

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A03962-2
100 μg/vial

SM22 alpha (TAGLN) (NM_003186) Human Recombinant Protein

$1062
Cat # PROTQ01995
20 µg

Anti-SM22 alpha (TAGLN) Mouse Monoclonal Antibody [Clone ID: OTI8C8]

Human, Mouse, Rat

IF, IHC, WB

$523
Cat # M03962
100 µl

TAGLN Overview

Facts about Transgelin.

TAGLN 3D structure. Source: alphafold

Transgelin (TAGLN)

Actin cross-linking/gelling protein (By similarity). Involved in calcium interactions and contractile properties of the cell that may contribute to replicative senescence.

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Gene Information

Human
Gene Name:	TAGLN
Uniprot:	Q01995
Entrez:	6876

Family

Belongs to:

calponin family

Alternative Names

DKFZp686P11128; Protein WS3-10; SM22 alpha; SM2222 kDa actin-binding protein; SMCCDKFZp686B01212; Smooth muscle protein 22-alpha; TAGLN; TAGLN1; transgelin variant 2; Transgelin; WS3-10; WS3-10SM22-alpha

Molecular Weight

Mass (kDA):
22.611 kDA

Genomic Context


Human

Location:	11q23.3
Sequence:	11; NC_000011.10 (117199294..117207465)

Subcellular Localizations

Cytoplasm.

Diseases

Neoplasms
Malignant Neoplasms
Carcinoma
Retinoblastoma
Cell Transformation, Neoplastic
Mammary Neoplasms
Adenocarcinoma
Malignant Neoplasm Of Breast
Malignant Paraganglionic Neoplasm
Neoplasm Metastasis
Malignant Squamous Cell Neoplasm
Cell Invasion
Carcinogenesis

Metastatic Malignant Neoplasm To The Lymph Node
Prostatic Neoplasms
Tissue Adhesions
Hyperplasia
Leukemia
Lymphoma
Adenoma

Interacting Proteins

IGF1R
TINF2

Pathways

Cell Cycle
Cell Proliferation
Cell Growth
S Phase
Cell Cycle Arrest
Cell Differentiation
Senescence
Localization
Cell Death
Pathogenesis
G1 Phase
Oncogenesis
Reverse Transcription

Angiogenesis
Proteolysis
Cell Division
Smooth Muscle Cell Differentiation
Muscle Cell Differentiation
Transdifferentiation
Mitosis

PTMs

Phosphorylation
Cleavage
Acetylation
Methylation

Dephosphorylation
Ubiquitination
Biotinylation
Reduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TAGLN

References

PMID: 1520290 by Thweatt R., et al. A novel gene encoding a smooth muscle protein is overexpressed in senescent human fibroblasts.

PMID: 1872880 by Nishida W., et al. Gene cloning and nucleotide sequence of SM22 alpha from the chicken gizzard smooth muscle.

1 Publications of Boster Transgelin Antibodies & ELISA Kits

PubMed ID: PMID:28239811, The expression and significance of IL-6, IFN-γ, SM22α, and MMP-2 in rat model ...

*More publications can be found for each product on its corresponding product page