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Product Info Summary
| SKU: | A04259 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-STAU1 Antibody
SKU/Catalog Number
A04259
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-STAU1 Antibody (Catalog # A04259). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
STAU1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-STAU1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04259)
Host
Rabbit
Contents
STAU1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
STAU1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human STAU1. The immunogen is located within the last 50 amino acids of STAU1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
TSPY1L antibody is human and mouse reactive. At least three isoforms of TSPY1 are known to exist; this antibody will detect only TSPY1L.
Reactive Species
A04259 is reactive to STAU1 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
63182 MW
Background of Staufen
STAU1 is a member of a family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human STAU1 also contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. STAU1 has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER. STAU1 is also known to interact with influenza ribonucleoproteins NS1, NP, and PA and is required for efficient viral replication.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A04259 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
STAU1 antibody can be used for detection of STAU1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of STAU1 in rat brain tissue lysate with STAU1 antibody at (A) 1 and (B) 2 μg/mL.
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Immunohistochemistry of STAU1 in human brain tissue with STAU1 antibody at 10 μg/mL.
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Immunofluorescence of STAU1 in Human Brain cells with STAU1 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For STAU1 (Source: Uniprot.org, NCBI)
Gene Name
STAU1
Full Name
Double-stranded RNA-binding protein Staufen homolog 1
Weight
63182 MW
Alternative Names
STAU, STAU, Double-stranded RNA-binding protein Staufen homolog 1 STAU1 PPP1R150, STAU staufen double-stranded RNA binding protein 1 double-stranded RNA-binding protein Staufen homolog 1|protein phosphatase 1, regulatory subunit 150|staufen, RNA binding protein, homolog 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on STAU1, check out the STAU1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for STAU1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-STAU1 Antibody (A04259)
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