Product Info Summary
SKU: | A01087Y694-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse |
Host: | Rabbit |
Application: | IHC, WB |
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Product info
Product Name
Anti-Stat5 (Phospho-Y694) STAT5A Antibody
SKU/Catalog Number
A01087Y694-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Stat5 (Phospho-Y694) STAT5A Antibody catalog # A01087Y694-1. Tested in WB,IHC applications. This antibody reacts with Human,Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Stat5 (Phospho-Y694) STAT5A Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01087Y694-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant protein of human IL5.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01087Y694-1 is reactive to STAT5A in Human, Mouse
Applications
A01087Y694-1 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
90647 MW
Background of Stat5a
Involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. May represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. Interacts with the SH2 domain of Grb2. May phosphorylate the voltage-gated potassium channel protein Kv1.2. Its activation is highly correlated with the stimulation of c-Jun N-terminal kinase activity. Involved in osmotic stress-dependent SNCA 'Tyr-125' phosphorylation.
Gluck SL, et al. (2004) J Clin Invest; 114(12): 1696-1699
Benzing T, et al. (2001) Proc Natl Acad Sci U S A; 98(17): 9784-9789
Tian D, et al. (2002) Mol Cell Biol; 22(8): 2650-2662
Lu Z, et al. (2001) Mol Cell Biol; 21(12): 4016-4031
Krishnan HH, et al. (2006) J Virol; 80(3): 1167-1180
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:1,000-1:2,000
IHC: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-Stat5 (Phospho-Y694) STAT5A Antibody A01087Y694-1
Western blot analysis of Phospho-Stat5(Y694) on mouse liver lysates using anti-Phospho-Stat5(Y694) antibody at 1/1Protein Target Info & Infographic
Gene/Protein Information For STAT5A (Source: Uniprot.org, NCBI)
Gene Name
STAT5A
Full Name
Signal transducer and activator of transcription 5A
Weight
90647 MW
Superfamily
transcription factor STAT family
Alternative Names
MGF; STAT5; STAT5A signal transducer and activator of transcription 5A ; STAT5a/b STAT5A MGF, STAT5 signal transducer and activator of transcription 5A signal transducer and activator of transcription 5A|epididymis secretory sperm binding protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on STAT5A, check out the STAT5A Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for STAT5A: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Stat5 (Phospho-Y694) STAT5A Antibody (A01087Y694-1)
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