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Key=sku, value=PB9511
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Key=created_at, value=2015-06-25 18:14:33
Key=updated_at, value=2024-09-30 05:02:05
Key=mst_search_weight, value=0
Key=status, value=Enabled
Key=name, value=Anti-STAT3 Antibody Picoband®
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Key=host, value=Rabbit
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Key=badge, value=free-antibody-validation
Key=price, value=370.0000
Key=weight, value=1.0000
Key=meta_title, value=Anti-STAT3 Antibody Picoband | Bosterbio PB9511
Key=meta_description, value=Boster Bio Anti-STAT3 Antibody Picoband® catalog # PB9511. Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. Supplied as 100μg/vial in Lyophilized form antibody.
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Key=url_key, value=anti-stat3-picoband-trade-antibody-pb9511-boster
Key=url_path, value=anti-stat3-picoband-trade-antibody-pb9511-boster
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Key=image_label, value=Figure 1. Western blot analysis of STAT3 using anti-STAT3 antibody (PB9511).
Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 30 ug of sampl
Key=small_image_label, value=Figure 1. Western blot analysis of STAT3 using anti-STAT3 antibody (PB9511).
Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 30 ug of sampl
Key=thumbnail_label, value=Figure 1. Western blot analysis of STAT3 using anti-STAT3 antibody (PB9511).
Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 30 ug of sampl
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Key=size, value=100 μg/vial
Key=protein_name, value=Signal transducer and activator of transcription 3
Key=gene_full_name, value=Signal transducer and activator of transcription 3
Key=uniprot_id, value=P40763
Key=reconstitution, value=Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Key=applications, value=Flow Cytometry, IF, ICC, WB
Key=reactivity, value=Human, Mouse, Rat
Key=form, value=Lyophilized
Key=concentration, value=Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Key=cross_reactivity, value=No cross-reactivity with other proteins
Key=recommended_detection_systems, value=Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for ICC.
Key=source_company, value=Boster PB9511
Key=isotype, value=Rabbit IgG
Key=molecular_weight, value=88068 MW
Key=sample_size_available, value=30ug for $99, contact us for details
Key=related_product_skus, value=B0001-5,AR1156,AR0146
Key=product_category, value=Primary Antibodies
Key=research_category, value=Cancer, Cardiogenesis, Cardiovascular, Developmental Biology, Embryogenesis, Embryonic Stem Cells, Epigenetics and Nuclear Signaling, Hypertrophy, Intracellular, Nuclear Signaling, Nuclear Signaling Pathways, Signal Transduction, Signaling Pathway, Stem Cells, Surface Molecules, Transcription, Transcription Factors, Transcription Factors/Regulators
Key=clonality, value=Polyclonal
Key=swatch_image, value=/e/k/ek1137.png
Key=rating_value, value=100
Key=review_count, value=17
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Key=yoast_focus_keyword, value=CD68 antibody
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Key=cj_related_products, value=Janiceps:EK1436^Liver Regeneration:PA1124|PA1623|PB9141|M00458-1|M00458-Dyl550
Key=description, value=Boster Bio Anti-STAT3 Antibody Picoband® catalog # PB9511. Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key=short_description, value=Boster Bio Anti-STAT3 Antibody Picoband® catalog # PB9511. Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key=meta_keyword, value=Anti-STAT3 Antibody Picoband®
Key=contents, value=Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
Key=background, value=The transcription factor, signal transducer and activator of transcription-3 (STAT-3) is the most pleiotropic member of the signal transducer and activator of transcription (STAT) family of transcription factors and mediates pivotal responses for the cytokine family. The mouse STAT3 gene contains 24 exons and spans 30 kb. The translation initiation codon is in exon 2, and the stop codon is in exon 24. STAT3 is mapped to 17q21. It contributes to various physiological processes. Hepatic STAT-3 signaling is thus essential for normal glucose homeostasis and may provide new therapeutic targets for diabetes mellitus.
Key=gene_name, value=STAT3
Key=synonyms, value=Signal transducer and activator of transcription 3;Acute-phase response factor;STAT3;APRF;
Key=application_details, value=Western blot, 0.1-0.5 μg/ml, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Flow Cytometry(Fixed), 1-3 μg/1x10⁶ cells, Human, Rat

Key=subcellular_localization, value= Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm. Translocated into the nucleus upon tyrosine phosphorylation and dimerization, in response to signaling by activated FGFR1, FGFR2, FGFR3 or FGFR4. Constitutive nuclear presence is independent of tyrosine phosphorylation. Predominantly present in the cytoplasm without stimuli. Upon leukemia inhibitory factor (LIF) stimulation, accumulates in the nucleus. The complex composed of BART and ARL2 plays an important role in the nuclear translocation and retention of STAT3. Identified in a complex with LYN and PAG1.
Key=sequence_similarities, value=Belongs to the transcription factor STAT family.
Key=tissue_specificity, value= Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Key=protein_function, value= Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)- responsive elements identified in the promoters of various acute- phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity). .
Key=application_notes, value=Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Key=competitor_equivalent_skus, value=sc 483|sc 7179|sc 8019|sc 482|sc 81001|sc 293151|sc 483 X|sc 7179 X|sc 8019 X|sc 482 X
Key=immunogen, value=A synthetic peptide corresponding to a sequence at the N-terminus of human STAT3, identical to the related mouse and rat sequences.
Key=purification, value=Immunogen affinity purified.
Key=storage, value=Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Key=custom_attribute_1, value=88 kDa
Key=custom_attribute_2, value=WB: human HEL whole cell lysates, human A549 whole cell lysates, human Hacat whole cell lysates, human U251 whole cell lysates, human K562 whole cell lysates, human SiHa whole cell lysates, human RT4 whole cell lysates, rat lung tissue lysates, rat heart tissue lysates, mouse lung tissue lysates, mouse heart tissue lysates
ICC/IF: A549 cell, U2OS cell
FCM: SiHa cell, PC-12 cell
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