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Product Info Summary
| SKU: | A10564 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-SLIT and NTRK-like protein 5 Slitrk5 Antibody
SKU/Catalog Number
A10564
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-SLIT and NTRK-like protein 5 Slitrk5 Antibody (Catalog # A10564). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Slitrk5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-SLIT and NTRK-like protein 5 Slitrk5 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A10564)
Host
Rabbit
Contents
Slitrk5 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Slitrk5 antibody was raised against a 14 amino acid synthetic peptide from near the center of human Slitrk5. The immunogen is located within amino acids 310 - 360 of Slitrk5.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
This antibody is predicted to have no cross-reactivity to other Slitrk proteins.
Reactive Species
A10564 is reactive to SLITRK5 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
107486 MW
Background of SLITRK5
SLIT and NTRK-like family 5 (Slitrk5) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk5 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A10564 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Slitrk5 antibody can be used for detection of Slitrk5 by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 5 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of Slitrk5 in 3T3 cell lysate with Slitrk5 antibody at 1 μg/mL in the (A) absence or (B) presence of blocking peptide.
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Immunohistochemistry of Slitrk4 in human brain tissue with Slitrk4 antibody at 2.5 μg/mL.
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Immunofluorescence of Slitrk5 in Human Brain cells with Slitrk5 antibody at 5 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For SLITRK5 (Source: Uniprot.org, NCBI)
Gene Name
SLITRK5
Full Name
SLIT and NTRK-like protein 5
Weight
107486 MW
Superfamily
SLITRK family
Alternative Names
LRRC11, bA364G4.2, KIAA0918, LRRC11, SLIT and NTRK-like protein 5, Leucine-rich repeat-containing protein 11 SLITRK5 LRRC11, bA364G4.2 SLIT and NTRK like family member 5 SLIT and NTRK-like protein 5|leucine rich repeat containing 11|leucine-rich repeat-containing protein 11|slit and trk like gene 5
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SLITRK5, check out the SLITRK5 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SLITRK5: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-SLIT and NTRK-like protein 5 Slitrk5 Antibody (A10564)
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