Anti-SLCO1B1/Oatp2 Antibody

Product Name

Anti-SLCO1B1/Oatp2 Antibody

View all SLCO1B1 Antibodies

SKU/Catalog Number

A01375

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-SLCO1B1/Oatp2 Antibody (Catalog # A01375). Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-SLCO1B1/Oatp2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01375)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human SLCO1B1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A01375 is reactive to SLCO1B1 in Human

Applications

A01375 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

76449 MW

Background of SLCO1B1

Mediates the Na+-independent uptake of organic anions such as pravastatin, taurocholate, methotrexate, dehydroepiandrosterone sulfate, 17-beta-glucuronosyl estradiol, estrone sulfate, prostaglandin E2, thromboxane B2, leukotriene C3, leukotriene E4, thyroxine and triiodothyronine. Involved in the clearance of bile acids and organic anions from the liver.

Kirchgessner T.G., J. Biol. Chem. 274:37161-37168(1999).
Keppler D., J. Biol. Chem. 275:23161-23168(2000).
Venter J.C., Submitted (JUL-2005).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000

Validation Images & Assay Conditions

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Western blot analysis of extracts from COLO205 and Jurkat cells, using SLCO1B1 antibody A01375.

Gene/Protein Information For SLCO1B1 (Source: Uniprot.org, NCBI)

Alternative Names

HBLRR; LST1; LST-1; LST-2; LST3; LST-3TM13; OATP1B1; OATP1B3; OATP2; OATP8; OATP-8; OATPC; OATP-C; SLC21A6; SLC21A8; SLCO1B1 solute carrier organic anion transporter family, member 1B1 SLCO1B1 HBLRR, LST-1, LST1, OATP-C, OATP1B1, OATP2, OATPC, SLC21A6 solute carrier organic anion transporter family member 1B1 solute carrier organic anion transporter family member 1B1|OATP-2|liver-specific organic anion transporter 1|sodium-independent organic anion-transporting polypeptide 2|solute carrier family 21 (organic anion transporter), member 6

For more info on SLCO1B1, check out the SLCO1B1 Infographic

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In this infographic, you will see the following information for SLCO1B1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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