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Product Info Summary
| SKU: | A04749 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-SLC29A3 Antibody
SKU/Catalog Number
A04749
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-SLC29A3 Antibody (Catalog # A04749). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
SLC29A3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-SLC29A3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04749)
Host
Rabbit
Contents
SLC29A3 antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
SLC29A3 antibody was raised against a 19 amino acid peptide near the amino terminus of human SLC29A3. The immunogen is located within the first 50 amino acids of SLC29A3.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
SLC29A3 antibody is human, mouse and rat reactive. At least two isoforms of SLC29A3 are known to exist; this antibody will detect both isoforms. SLC29A3 antibody is predicted to not cross-react with other SLC29 proteins.
Reactive Species
A04749 is reactive to SLC29A3 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
51815 MW
Background of SLC29A3
SLC29A3 is a member of the equilibrative nucleoside transporter family which plays a key role in nucleoside and nucleobase uptake for salvage pathways of nucleotide synthesis (1,2). SLC29A3 is a transmembrane glycoprotein that localizes to the lysosomal membrane and is a broad selectivity, low affinity nucleoside transporter (3). Mutations in the SLC29A3 gene have been associated with H syndrome, which is characterized by cutaneous hyperpigmentation and hypertrichosis, hepatosplenomegaly, heart anomalies, and hypogonadism (4). A related disorder, PHID (pigmented hypertrichosis with insulin-dependent diabetes mellitus), has also been associated with mutations at this locus (5).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A04749 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
SLC29A3 antibody can be used for detection of SLC29A3 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of SLC29A3 in mouse bladder tissue lysate with SLC29A3 antibody at (A) 1 and (B) 2 μg/ml.
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Immunohistochemistry of SLC29A3 in rat colon tissue with SLC29A3 antibody at 5 μg/mL.
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Immunofluorescence of SLC29A3 in rat colon muscle tissue with SLC29A3 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For SLC29A3 (Source: Uniprot.org, NCBI)
Gene Name
SLC29A3
Full Name
Equilibrative nucleoside transporter 3
Weight
51815 MW
Superfamily
SLC29A/ENT transporter (TC 2.A.57) family
Alternative Names
Solute carrier family 29 member 3, Equilibrative nucleoside transporter 3, ENT3, HCLAP, HJCD, PHID SLC29A3 ENT3, HCLAP, HJCD, PHID solute carrier family 29 member 3 equilibrative nucleoside transporter 3|solute carrier family 29 (equilibrative nucleoside transporter), member 3|solute carrier family 29 (nucleoside transporters), member 3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SLC29A3, check out the SLC29A3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SLC29A3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-SLC29A3 Antibody (A04749)
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