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Product Info Summary
| SKU: | A12227 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-SIPA1L2 Antibody
SKU/Catalog Number
A12227
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-SIPA1L2 Antibody (Catalog # A12227). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
SIPA1L2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-SIPA1L2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12227)
Host
Rabbit
Contents
SIPA1L2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
SIPA1L2 antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human SIPA1L2. The immunogen is located within the first 50 amino acids of SIPA1L2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
UHRF1BP1 antibody is predicted to not cross-react with UHRF1BP1L
Reactive Species
A12227 is reactive to SIPA1L2 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
190438 MW
Background of SIPA1L2
Signal-induced proliferation associated-like protein 2 (SIPA1L2) is a member of the SIPA1 family of RapGAPs. Little is known of the role of the SIPA1L2 protein, but recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is likely that SIPA1L2 plays a role in embryo development and cell proliferation, possibly including oncogenesis.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A12227 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
SIPA1L2 antibody can be used for detection of SIPA1L2 by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of SIPA1L2 in rat brain tissue lysate with SIPA1L2 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
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Immunohistochemistry of SIPA1L2 in human brain tissue with SIPA1L2 antibody at 5 μg/mL.
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Immunofluorescence of SIPA1L2 in human brain tissue with SIPA1L2 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For SIPA1L2 (Source: Uniprot.org, NCBI)
Gene Name
SIPA1L2
Full Name
Signal-induced proliferation-associated 1-like protein 2
Weight
190438 MW
Alternative Names
SPAL2, KIAA1389, Signal-induced proliferation-associated 1-like protein 2, SIPA1-like protein 2 SIPA1L2 SPAL2, SPAR2 signal induced proliferation associated 1 like 2 signal-induced proliferation-associated 1-like protein 2|SIPA1-like protein 2|SPA-1-like 2|spine-associated RapGAP 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SIPA1L2, check out the SIPA1L2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SIPA1L2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-SIPA1L2 Antibody (A12227)
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