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Key=meta_description, value=Boster Bio Anti-SBP/SELENBP1 Antibody catalog # PA2216. Tested in IHC, WB applications. This antibody reacts with Human. Supplied as 100μg/vial in Lyophilized form antibody.
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Lane 1: COLO320 Cell Lysate
Lane 2: PANC Cell Lysate
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Lane 1: COLO320 Cell Lysate
Lane 2: PANC Cell Lysate
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Lane 1: COLO320 Cell Lysate
Lane 2: PANC Cell Lysate
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Key=concentration, value=Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Key=cross_reactivity, value=No cross-reactivity with other proteins
Key=recommended_detection_systems, value=Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
Key=predicted_reactivity
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Key=isotype, value=Rabbit IgG
Key=molecular_weight, value=52391 MW
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Key=description, value=Boster Bio Anti-SBP/SELENBP1 Antibody catalog # PA2216. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key=short_description, value=Boster Bio Anti-SBP/SELENBP1 Antibody catalog # PA2216. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key=meta_keyword, value=Anti-SBP/SELENBP1 Antibody
Key=contents, value=Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Key=background, value=Selenium-binding protein 1, also known as SELENBP1 or SBP is a protein that in humans is encoded by the SLELNBP1 gene. This gene is mapped to 1q21.3. This gene encodes a member of the selenium-binding protein family. Selenium is an essential nutrient that exhibits potent anticarcinogenic properties, and deficiency of selenium may cause certain neurologic diseases. The effects of selenium in preventing cancer and neurologic diseases may be mediated by selenium-binding proteins, and decreased expression of this gene may be associated with several types of cancer. The encoded protein may play a selenium-dependent role in ubiquitination/deubiquitination-mediated protein degradation.
Key=gene_name, value=SELENBP1
Key=synonyms, value=Selenium-binding protein 1;56 kDa selenium-binding protein;SBP56;SP56;SELENBP1;SBP;
Key=application_details, value=Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat
Western blot, 0.1-0.5μg/ml, Human

Key=subcellular_localization, value= Nucleus. Cytoplasm, cytosol. Membrane ; Peripheral membrane protein . May associate with Golgi membrane. May associate with the membrane of autophagosomes (By similarity). .
Key=sequence_similarities, value=Belongs to the PIAS family.
Key=tissue_specificity, value= Highly expressed in liver, lung, colon, prostate, kidney and pancreas. In brain, present both in neurons and glia (at protein level). Down-regulated in lung adenocarcinoma, colorectal carcinoma and ovarian cancer. Two-fold up-regulated in brain and blood from schizophrenia patients. .
Key=protein_function, value= Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport (By similarity). .
Key=application_notes, value=Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
Key=competitor_equivalent_skus, value=sc 160790|sc 160788|sc 373726|sc 367809
Key=immunogen, value=A synthetic peptide corresponding to a sequence in the middle region of human Selenium Binding Protein 1.
Key=purification, value=Immunogen affinity purified.
Key=storage, value=Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Key=custom_attribute_1, value=57 kDa
Key=custom_attribute_2, value=WB: COLO320 Cell, PANC Cell
IHC: Human Liver Cancer Tissue
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Anti-SBP/SELENBP1 Antibody Picoband®

SELENBP1 antibody

Boster Bio Anti-SBP/SELENBP1 Antibody catalog # PA2216. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Info Summary

SKU: PA2216
Size: 100 μg/vial
Reactive Species: Human
Host: Rabbit
Application: IHC, WB

Product Name

Anti-SBP/SELENBP1 Antibody Picoband®

View all SELENBP1 Antibodies

SKU/Catalog Number

PA2216

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-SBP/SELENBP1 Antibody catalog # PA2216. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-SBP/SELENBP1 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2216)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human Selenium Binding Protein 1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA2216 is reactive to SELENBP1 in Human

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

57 kDa

Calculated molecular weight

52391 MW

Background of SELENBP1

Selenium-binding protein 1, also known as SELENBP1 or SBP is a protein that in humans is encoded by the SLELNBP1 gene. This gene is mapped to 1q21.3. This gene encodes a member of the selenium-binding protein family. Selenium is an essential nutrient that exhibits potent anticarcinogenic properties, and deficiency of selenium may cause certain neurologic diseases. The effects of selenium in preventing cancer and neurologic diseases may be mediated by selenium-binding proteins, and decreased expression of this gene may be associated with several types of cancer. The encoded protein may play a selenium-dependent role in ubiquitination/deubiquitination-mediated protein degradation.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Applications

PA2216 is guaranteed for IHC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat
Western blot, 0.1-0.5μg/ml, Human

Positive Control

WB: COLO320 Cell, PANC Cell
IHC: Human Liver Cancer Tissue

Validation Images & Assay Conditions

Gene/Protein Information For SELENBP1 (Source: Uniprot.org, NCBI)

Gene Name

SELENBP1

Full Name

Methanethiol oxidase

Weight

52391 MW

Superfamily

selenium-binding protein family

Alternative Names

Selenium-binding protein 1;56 kDa selenium-binding protein;SBP56;SP56;SELENBP1;SBP; SELENBP1 EHMTO, HEL-S-134P, LPSB, MTO, SBP56, SP56, hSBP selenium binding protein 1 methanethiol oxidase|56 kDa selenium-binding protein|epididymis secretory sperm binding protein Li 134P

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on SELENBP1, check out the SELENBP1 Infographic

SELENBP1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for SELENBP1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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3 Customer Q&As for Anti-SBP/SELENBP1 Antibody Picoband®

Question

Will anti-Selenium Binding Protein 1/SELENBP1 antibody PA2216 work for WB with mucosa of transverse colon?

Verified Customer

Verified customer

Asked: 2020-01-29

Answer

According to the expression profile of mucosa of transverse colon, SELENBP1 is highly expressed in mucosa of transverse colon. So, it is likely that anti-Selenium Binding Protein 1/SELENBP1 antibody PA2216 will work for WB with mucosa of transverse colon.

Boster Scientific Support

Answered: 2020-01-29

Question

We are currently using anti-Selenium Binding Protein 1/SELENBP1 antibody PA2216 for human tissue, and we are content with the WB results. The species of reactivity given in the datasheet says human. Is it possible that the antibody can work on canine tissues as well?

D. Parker

Verified customer

Asked: 2016-03-25

Answer

The anti-Selenium Binding Protein 1/SELENBP1 antibody (PA2216) has not been tested for cross reactivity specifically with canine tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in canine you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2016-03-25

Question

We need to test anti-Selenium Binding Protein 1/SELENBP1 antibody PA2216 on human mucosa of transverse colon for research purposes, then I may be interested in using anti-Selenium Binding Protein 1/SELENBP1 antibody PA2216 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?

R. Collins

Verified customer

Asked: 2013-02-26

Answer

The products we sell, including anti-Selenium Binding Protein 1/SELENBP1 antibody PA2216, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.

Boster Scientific Support

Answered: 2013-02-26

Order DetailsPrice
PA2216

100μg

$370
PA2216-10ug

10μg sample (liquid)

$99
PA2216-Biotin

100 μg Biotin conjugated

$570
PA2216-Cy3

100 μg Cy3 conjugated

$570
PA2216-Dylight488

100 μg Dylight488 conjugated

$570
PA2216-Dylight550

100 μg Dylight550 conjugated

$570
PA2216-Dylight594

100 μg Dylight594 conjugated

$570
PA2216-FITC

100 μg FITC conjugated

$570
PA2216-HRP

100 μg HRP conjugated

$570
PA2216-APC

100 μg APC conjugated

$670
PA2216-PE

100 μg PE conjugated

$670
PA2216-iFluor647

100 μg iFluor647 conjugated

$670
PA2216-carrier-free

Carrier Free

$370

More conjugates/formats

Free Secondary Antibody

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PA2216
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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