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Product Info Summary
| SKU: | A31733 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-SDPR CAVIN2 Antibody
SKU/Catalog Number
A31733
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-SDPR CAVIN2 Antibody (Catalog # A31733). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human.
Storage & Handling
SDPR antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-SDPR CAVIN2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A31733)
Host
Rabbit
Contents
SDPR Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Rabbit polyclonal SDPR antibody was raised against an 18 amino acid peptide near the amino terminus of human SDPR. The immunogen is located within the first 50 amino acids of SDPR.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
It is predicted to not cross-react with other members of the cavin family.
Reactive Species
A31733 is reactive to SDPR in Human
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
47173 MW
Background of CAVIN2
The serum deprivation-response protein (SDPR) is a calcium-independent phospholipid-binding protein whose expression is increased in serum-starved cells. SDPR is a substrate for protein kinase C (PKC) phosphorylation and recruits the polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation. Both SDPR and PTRF, as well as the other member of the cavin family PRKCDBP were down regulated in breast cancer cell lines and breast tumor tissue, suggesting that expression of the cavin family proteins could be a useful prognostic indicator of breast cancer progression.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A31733 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
SDPR antibody can be used for detection of SDPR by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of SDPR in HeLa cell lysate with SDPR antibody at (A) 1 and (B) 2 μg/mL
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Immunohistochemistry of SDPR in human spleen tissue with SDPR antibody at 5 μg/ml.
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Immunofluorescence of SDPR in human spleen tissue with SDPR antibody at 20 μg/ml.
Protein Target Info & Infographic
Gene/Protein Information For SDPR (Source: Uniprot.org, NCBI)
Gene Name
SDPR
Full Name
Caveolae-associated protein 2
Weight
47173 MW
Superfamily
CAVIN family
Alternative Names
SDR, CAVIN2, PS-p68, cavin-2, Serum deprivation-response protein, Cavin-2 CAVIN2 PS-p68, SDPR, SDR, cavin-2 caveolae associated protein 2 caveolae-associated protein 2|phosphatidylserine-binding protein|serum deprivation response|serum deprivation-response protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SDPR, check out the SDPR Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SDPR: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-SDPR CAVIN2 Antibody (A31733)
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No publications found for A31733
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