Anti-SCP3/SYCP3 Antibody Picoband®

Product Name

Anti-SCP3/SYCP3 Antibody Picoband®

View all SCP3/SYCP3 Antibodies

SKU/Catalog Number

RP1035

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-SCP3/SYCP3 Antibody catalog # RP1035. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-SCP3/SYCP3 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # RP1035)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human SCP3 recombinant protein (Position: E18-E223). Human SCP3 shares 72% and 73% amino acid (aa) sequences identity with mouse and rat SCP3, respectively.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

RP1035 is reactive to SYCP3 in Human

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

28 kDa

Calculated molecular weight

27729 MW

Background of SCP3/SYCP3

SYCP3, also known as COR1 or SCP3, is a protein that in humans is encoded by the SYCP3 gene. It is mapped to 12q23.2. This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein. SYCP3 has an essential meiotic function in human spermatogenesis that is compromised by the mutant protein by dominant-negative interference. SYCP3 is linked to inherited aneuploidy in female germ cells and provides a model system for studying age-dependent degeneration in oocytes.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

RP1035 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human

Positive Control

WB: HT1080 Whole Cell

Validation Images & Assay Conditions

Gene/Protein Information For SYCP3 (Source: Uniprot.org, NCBI)

Alternative Names

Synaptonemal complex protein 3;SCP-3;SYCP3;SCP3; Sycp3|Co, Cor1, Sc, Scp3|synaptonemal complex protein 3|synaptonemal complex protein 3|SCP-3

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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