Product Info Summary
SKU: | A09448 |
---|---|
Size: | 100 µl |
Reactive Species: | Human |
Host: | Rabbit |
Application: | IF |
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Product info
Product Name
Anti-SCN7A Antibody
SKU/Catalog Number
A09448
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-SCN7A Antibody (Catalog # A09448). Tested in IF applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-SCN7A Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09448)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human SCN7A.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A09448 is reactive to SCN7A in Human
Reconstitution
Calculated molecular weight
193493 MW
Background of SCN7A
Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient.
George A.L. Jr., Proc. Natl. Acad. Sci. U.S.A. 89:4893-4897(1992).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A09448 is guaranteed for IF Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Immunofluorescence: 1:100~1:500
Validation Images & Assay Conditions
Click image to see more details
Immunofluorescence analysis of A549 cells, using SCN7A antibody A09448.
Protein Target Info & Infographic
Gene/Protein Information For SCN7A (Source: Uniprot.org, NCBI)
Gene Name
SCN7A
Full Name
Sodium channel protein type 7 subunit alpha
Weight
193493 MW
Superfamily
sodium channel (TC 1.A.1.10) family
Alternative Names
Sodium channel protein type 7 subunit alpha;Putative voltage-gated sodium channel subunit alpha Nax;Sodium channel protein cardiac and skeletal muscle subunit alpha;Sodium channel protein type VII subunit alpha;SCN7A;SCN6A; SCN7A NaG, Nav2.1, Nav2.2, SCN6A sodium voltage-gated channel alpha subunit 7 sodium channel protein type 7 subunit alpha|putative voltage-gated sodium channel subunit alpha Nax|sodium channel protein cardiac and skeletal muscle subunit alpha|sodium channel protein type VII subunit alpha|sodium channel, voltage-gated, type VI, alpha polypeptide|sodium channel, voltage-gated, type VII, alpha subunit|voltage-dependent sodium channel alpha subunit
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SCN7A, check out the SCN7A Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SCN7A: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-SCN7A Antibody (A09448)
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No publications found for A09448
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Customer Q&As
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4 Customer Q&As for Anti-SCN7A Antibody
Question
We are currently using anti-SCN7A antibody A09448 for human tissue, and we are content with the IF results. The species of reactivity given in the datasheet says human. Is it possible that the antibody can work on zebrafish tissues as well?
Verified Customer
Verified customer
Asked: 2019-07-04
Answer
The anti-SCN7A antibody (A09448) has not been tested for cross reactivity specifically with zebrafish tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in zebrafish you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2019-07-04
Question
I see that the anti-SCN7A antibody A09448 works with IF, what is the protocol used to produce the result images on the product page?
Verified Customer
Verified customer
Asked: 2018-05-31
Answer
You can find protocols for IF on the "support/technical resources" section of our navigation menu. If you have any further questions, please send an email to [email protected]
Boster Scientific Support
Answered: 2018-05-31
Question
We need to test anti-SCN7A antibody A09448 on human fetal skeletal muscle heart for research purposes, then I may be interested in using anti-SCN7A antibody A09448 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?
Verified Customer
Verified customer
Asked: 2018-04-27
Answer
The products we sell, including anti-SCN7A antibody A09448, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.
Boster Scientific Support
Answered: 2018-04-27
Question
Is a blocking peptide available for product anti-SCN7A antibody (A09448)?
D. Johnson
Verified customer
Asked: 2017-03-30
Answer
We do provide the blocking peptide for product anti-SCN7A antibody (A09448). If you would like to place an order for it please contact [email protected] and make a special request.
Boster Scientific Support
Answered: 2017-03-30