Anti-Ribonuclease A/RNASE1 Antibody Picoband®

Product Name

Anti-Ribonuclease A/RNASE1 Antibody Picoband®

View all Ribonuclease A Antibodies

SKU/Catalog Number

PA1507

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Ribonuclease A/RNASE1 Antibody catalog # PA1507. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Ribonuclease A/RNASE1 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1507)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human Ribonuclease A.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA1507 is reactive to RNASE1 in Human

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

18 kDa

Calculated molecular weight

17644 MW

Background of Ribonuclease A

RIBONUCLEASE A FAMILY, 1 (Ribonuclease pancreatic) is an enzyme that in humans is encoded by the RNASE1 gene. By genomic sequence analysis, RNASE1 gene is mapped the to chromosome 14q11.2, where it is linked to 7 other RNase A superfamily genes. Monomeric human pancreatic RNase, devoid of any biological activity other than its RNA degrading ability, was engineered into a dimeric protein with a cytotoxic action on mouse and human tumor cells, but lacking any appreciable toxicity on mouse and human normal cells. This dimeric variant of human pancreas RNase selectively sensitizes to apoptotic death cells derived from a human thyroid tumor. Because of its selectivity for tumor cells, and because of its human origin, this protein represents a potentially very attractive, novel tool for anticancer therapy.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PA1507 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human

Positive Control

WB: MCF-7 Whole Cell, U87 Whole Cell, HELA Whole Cell, MM231 Whole Cell, JURKAT Whole Cell, SMMC Whole Cell, COLO320 Whole Cell, SW620 Whole Cell, CEM Whole Cell

Validation Images & Assay Conditions

Gene/Protein Information For RNASE1 (Source: Uniprot.org, NCBI)

Alternative Names

Ribonuclease pancreatic;3.1.27.5;HP-RNase;RIB-1;RNase UpI-1;Ribonuclease 1;RNase 1;Ribonuclease A;RNase A;RNASE1;RIB1, RNS1; RNASE1 RAC1, RIB1, RNS1 ribonuclease A family member 1, pancreatic ribonuclease pancreatic|HP-RNase|RIB-1|RNase 1|RNase A|RNase upI-1|ribonuclease 1|ribonuclease A C1|ribonuclease, RNase A family, 1 (pancreatic)

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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