Product Info Summary
SKU: | A01880 |
---|---|
Size: | 100 µl |
Reactive Species: | Human |
Host: | Rabbit |
Application: | IF |
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Product info
Product Name
Anti-Rel (Ab-503) Antibody
SKU/Catalog Number
A01880
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-Rel (Ab-503) Antibody (Catalog # A01880). Tested in IF applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Rel (Ab-503) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01880)
Host
Rabbit
Contents
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Peptide sequence around aa.501~505 (T-S-S-D-S) derived from Human Rel.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A01880 is reactive to REL in Human
Reconstitution
Observed Molecular Weight
39 kDa
Calculated molecular weight
42848 MW
Background of c-Rel
The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA (MIM 164014), RELB (604758), NFKB1 (MIM 164011), and NFKB2 (MIM 164012). These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor (MIM 164008) (Belguise and Sonenshein, 2007 (PubMed18037997)).
Copley RR et al. (2007) Genome Res. 17(9):1327-35.
Liu YW,et al.(2007) Cell Mol Life Sci. 64(24):3282-94.
Banerjee D, (2005) Immunity. 23(4):445-58.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A01880 is guaranteed for IF Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Predicted MW: 78kd
Immunofluorescence: 1:100~1:200
Validation Images & Assay Conditions
Click image to see more details
Immunofluorescence staining of methanol-fixed Hela cells using Rel(Ab-503) Antibody #A01880.
Protein Target Info & Infographic
Gene/Protein Information For REL (Source: Uniprot.org, NCBI)
Gene Name
REL
Full Name
Proto-oncogene c-Rel
Weight
42848 MW
Alternative Names
Platelet-derived growth factor D;PDGF-D;Iris-expressed growth factor;Spinal cord-derived growth factor B;SCDGF-B;Platelet-derived growth factor D, latent form;PDGFD latent form;Platelet-derived growth factor D, receptor-binding form;PDGFD receptor-binding form;PDGFD;IEGF, SCDGFB;MSTP036, UNQ1899/PRO4345; REL C-Rel, HIVEN86A REL proto-oncogene, NF-kB subunit proto-oncogene c-Rel|oncogene REL, avian reticuloendotheliosis|v-rel avian reticuloendotheliosis viral oncogene homolog
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on REL, check out the REL Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for REL: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Rel (Ab-503) Antibody (A01880)
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No publications found for A01880
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Customer Q&As
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6 Customer Q&As for Anti-Rel (Ab-503) Antibody
Question
I see that the anti-Rel (Ab-503) antibody A01880 works with IF, what is the protocol used to produce the result images on the product page?
Verified Customer
Verified customer
Asked: 2020-03-19
Answer
You can find protocols for IF on the "support/technical resources" section of our navigation menu. If you have any further questions, please send an email to [email protected]
Boster Scientific Support
Answered: 2020-03-19
Question
Please see the WB image, lot number and protocol we used for colon using anti-Rel (Ab-503) antibody A01880. Please let me know if you require anything else.
Verified Customer
Verified customer
Asked: 2020-01-31
Answer
Thank you very much for the data. Our lab team are working to resolve this as quickly as possible, and we appreciate your patience and understanding! You have provided everything we needed. Please let me know if there is anything you need in the meantime.
Boster Scientific Support
Answered: 2020-01-31
Question
Does anti-Rel (Ab-503) antibody A01880 work on primate IF with colon?
Verified Customer
Verified customer
Asked: 2019-08-26
Answer
Our lab technicians have not tested anti-Rel (Ab-503) antibody A01880 on primate. You can run a BLAST between primate and the immunogen sequence of anti-Rel (Ab-503) antibody A01880 to see if they may cross-react. If the sequence homology is close, then you can perform a pilot test. Keep in mind that since we have not validated primate samples, this use of the antibody is not covered by our guarantee. However we have an innovator award program that if you test this antibody and show it works in primate colon in IF, you can get your next antibody for free.
Boster Scientific Support
Answered: 2019-08-26
Question
Would anti-Rel (Ab-503) antibody A01880 work for IF with colon?
Verified Customer
Verified customer
Asked: 2019-05-21
Answer
According to the expression profile of colon, REL is highly expressed in colon. So, it is likely that anti-Rel (Ab-503) antibody A01880 will work for IF with colon.
Boster Scientific Support
Answered: 2019-05-21
Question
I would like to test anti-Rel (Ab-503) antibody A01880 on human colon for research purposes, then I may be interested in using anti-Rel (Ab-503) antibody A01880 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?
Verified Customer
Verified customer
Asked: 2018-04-02
Answer
The products we sell, including anti-Rel (Ab-503) antibody A01880, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.
Boster Scientific Support
Answered: 2018-04-02
Question
I was wanting to use your anti-Rel (Ab-503) antibody for IF for human colon on frozen tissues, but I want to know if it has been validated for this particular application. Has this antibody been validated and is this antibody a good choice for human colon identification?
R. Williams
Verified customer
Asked: 2014-11-07
Answer
You can see on the product datasheet, A01880 anti-Rel (Ab-503) antibody has been validated for IF on human tissues. We have an innovator award program that if you test this antibody and show it works in human colon in IHC-frozen, you can get your next antibody for free.
Boster Scientific Support
Answered: 2014-11-07