Anti-RCL1 Antibody

Product Name

Anti-RCL1 Antibody

View all RCL1 Antibodies

SKU/Catalog Number

A12027

Size

100μl

Form

Liquid

Description

Boster Bio Anti-RCL1 Antibody catalog # A12027. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-RCL1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12027)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Monoclonal

Clone Number

F7E4

Isotype

IgG

Immunogen

Synthesized peptide derived from the C-terminal region of human RCL1. at AA rangle: 300-380

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A12027 is reactive to RCL1 in Human, Mouse, Rat

Applications

A12027 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

40843 MW

Background of RCL1

COBRA1 (cofactor of BRCA1) also known as NELF-B, is an essential component of the negative elongation factor (NELF) complex. COBRA1 has been shown to directly bind estrogen receptor alpha (ERα) and repress ERα-mediated transcription (Aiyar SE et al., 2004). COBRA1 has also been demonstrated to interact with c-Jun and c-Fos suggesting a role in modulation of the AP-1 pathway and therefore may be important in cell proliferation, differentiation, apoptosis and oncogenesis (Zhong H et al., 2004)

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000

Validation Images & Assay Conditions

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Western Blot (WB) analysis of HuvEc cells using RCL1 Polyclonal antibody.

Gene/Protein Information For RCL1 (Source: Uniprot.org, NCBI)

Alternative Names

RNA terminal phosphate cyclase-like 1,2310040A02Rik RCL1 RNAC, RPCL1 RNA terminal phosphate cyclase like 1 RNA 3-terminal phosphate cyclase-like protein|RNA cyclase homolog

For more info on RCL1, check out the RCL1 Infographic

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In this infographic, you will see the following information for RCL1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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