Product Info Summary
SKU: | A03977 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human |
Host: | Rabbit |
Application: | ELISA, WB |
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Product info
Product Name
Anti-PTPRD Antibody
SKU/Catalog Number
A03977
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-PTPRD Antibody (Catalog # A03977). Tested in ELISA, WB applications. This antibody reacts with Human.
Storage & Handling
PTPRD antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-PTPRD Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03977)
Host
Rabbit
Contents
PTPRD Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
PTPRD antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human PTPRD. The immunogen is located within the first 50 amino acids of PTPRD.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
PTPRD antibody is human specific. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. PTPRD cleavage products are often observed in vivo
Reactive Species
A03977 is reactive to PTPRD in Human
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
214760 MW
Background of PTPRD
PTPRD (Protein tyrosine phosphatase receptor type D) is a member of the protein tyrosine phosphatase (PTP) family that plays diverse roles during development including cell growth, differentiation, mitotic cycle and oncogenic transformation. PTPRD contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains. The extracellular region of PTPRD is composed of three Ig-like and eight fibronectin type III-like domains (1,3). PTPRD interacts with PPFIA1-3 and is a tumor suppressor on chromosome 9p that is involved in the development of glioblastoma multiforme (GBMs) and multiple human cancers.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A03977 is guaranteed for ELISA, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
PTPRD antibody can be used for detection of PTPRD by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of PTPRD in HeLa cell lysate with PTPRD antibody at 1 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For PTPRD (Source: Uniprot.org, NCBI)
Gene Name
PTPRD
Full Name
Receptor-type tyrosine-protein phosphatase delta
Weight
214760 MW
Superfamily
protein-tyrosine phosphatase family
Alternative Names
HPTP, PTPD, HPTPD, HPTPDELTA, RPTPDELTA, Receptor-type tyrosine-protein phosphatase delta, Protein-tyrosine phosphatase delta PTPRD HPTP, HPTPD, HPTPDELTA, PTPD, R-PTP-delta, RPTPDELTA protein tyrosine phosphatase receptor type D receptor-type tyrosine-protein phosphatase delta|protein tyrosine phosphatase, receptor type, delta polypeptide|rceptor-type tyrosine-protein phosphatase delta
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PTPRD, check out the PTPRD Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PTPRD: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-PTPRD Antibody (A03977)
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