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Product Info Summary
| SKU: | A11841 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Rat |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-PRTFDC1 Antibody
SKU/Catalog Number
A11841
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-PRTFDC1 Antibody (Catalog # A11841). Tested in ELISA, WB applications. This antibody reacts with Human, Rat.
Storage & Handling
PRTFDC1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-PRTFDC1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A11841)
Host
Rabbit
Contents
PRTFDC1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
PRTFDC1 antibody was raised against a 14 amino acid synthetic peptide from near the center of human PRTFDC1. The immunogen is located within amino acids 90 - 140 of PRTFDC1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
KPNA7 antibody is human specific. KPNA7 antibody is predicted to not cross-react with other Importin alpha family members.
Reactive Species
A11841 is reactive to PRTFDC1 in Human, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
25674 MW
Background of PRTFDC1
Phosphoribosyl transferase domain containing 1 (PRTFDC1) is highly homologous to the hypoxanthine phosphoribosyltransferase (HPRT1) and may have arisen from a gene duplication event of a common ancestor gene. Recently, it was shown that CpG islands in the PRTFDC1 promoter could be hypermethylated in ovarian cancers and oral squamous-cell carcinomas (OSCC), leading to gene silencing. Restoration of PRTFDC1 expression in OSCC inhibited cell growth in colony-formation assays, while knockdown of PRTFDC1 expression in OSCC that expressed the gene promoted cell growth. These results suggest that PRTFDC1 can act as a tumor-suppressor gene. At least three isoforms of PRTFDC1 are known to exist.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A11841 is guaranteed for ELISA, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
PRTFDC1 antibody can be used for detection of PRTFDC1 by Western blot at 1 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of PRTFDC1 in human brain tissue lysate with PRTFDC1 antibody at 1 μg/mL in the (A) absence and (B) presence of blocking peptide.
Protein Target Info & Infographic
Gene/Protein Information For PRTFDC1 (Source: Uniprot.org, NCBI)
Gene Name
PRTFDC1
Full Name
Phosphoribosyltransferase domain-containing protein 1
Weight
25674 MW
Superfamily
purine/pyrimidine phosphoribosyltransferase family
Alternative Names
HHGP, HHGP, Phosphoribosyltransferase domain-containing protein 1 PRTFDC1 HHGP phosphoribosyl transferase domain containing 1 phosphoribosyltransferase domain-containing protein 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PRTFDC1, check out the PRTFDC1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PRTFDC1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-PRTFDC1 Antibody (A11841)
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