Anti-Proteasome subunit beta type-1 PSMB1 Antibody

Product Name

Anti-Proteasome subunit beta type-1 PSMB1 Antibody

View all Proteasome beta 1 Antibodies

SKU/Catalog Number

A06891

Size

100ul

Form

Liquid

Description

Boster Bio Anti-Proteasome subunit beta type-1 PSMB1 Antibody catalog # A06891. Tested in WB,ICC/IF applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Proteasome subunit beta type-1 PSMB1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06891)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human Rag A/B

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A06891 is reactive to PSMB1 in Human, Mouse, Rat

Applications

A06891 is guaranteed for IF, ICC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

26489 MW

Background of Proteasome beta 1

Location-regulated scaffold connecting MEK to RAF. Has very low protein kinase activity and can phosphorylate MAP2K1 at several Ser and Thr residues with very low efficiency (in vitro). Interaction with BRAF enhances KSR2-mediated phosphorylation of MAP2K1 (in vitro). Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.

Ota T., Nat. Genet. 36:40-45(2004).
Scherer S.E., Nature 440:346-351(2006).
Channavajhala P.L., J. Biol. Chem. 278:47089-47097(2003).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:2000
ICC/IF: 1:50-1:200

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For PSMB1 (Source: Uniprot.org, NCBI)

Alternative Names

EC 3.4.25.1; FLJ25321; HC5; KIAA1838; Macropain subunit C5; Multicatalytic endopeptidase complex subunit C5; PMSB1; proteasome (prosome, macropain) subunit, beta type, 1; proteasome beta 1 subunit; Proteasome component C5; Proteasome gamma chain; proteasome subunit beta type-1; proteasome subunit HC5; PSC5 PSMB1 HC5, PMSB1, PSC5 proteasome 20S subunit beta 1 proteasome subunit beta type-1|macropain subunit C5|multicatalytic endopeptidase complex subunit C5|proteasome (prosome, macropain) subunit, beta type, 1|proteasome beta 1 subunit|proteasome component C5|proteasome gamma chain|proteasome subunit HC5|proteasome subunit beta 1|proteasome subunit beta6|testicular secretory protein Li 45

For more info on PSMB1, check out the PSMB1 Infographic

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In this infographic, you will see the following information for PSMB1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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