Product Info Summary
SKU: | A01132T676 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse |
Host: | Rabbit |
Application: | ELISA, IHC |
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Product info
Product Name
Anti-Phospho-TTK (T676) Antibody
SKU/Catalog Number
A01132T676
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Phospho-TTK (T676) Antibody catalog # A01132T676. Tested in ELISA, IHC applications. This antibody reacts with Human, Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Phospho-TTK (T676) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01132T676)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human TTK around the phosphorylation site of T676.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01132T676 is reactive to TTK in Human, Mouse
Applications
A01132T676 is guaranteed for ELISA, IHC Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
97072 MW
Background of TTK
Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint.
Mills G.B., J. Biol. Chem. 267:16000-16006(1992).
Ota T., Nat. Genet. 36:40-45(2004).
Mungall A.J., Nature 425:805-811(2003)
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC 1:100-1:300
ELISA 1:20000
Validation Images & Assay Conditions
![a01132t676 anti phospho ttk t676 antibody ihc testing 1 a01132t676 anti phospho ttk t676 antibody ihc testing 1](https://www.bosterbio.com/media/catalog/product/a/0/a01132t676-anti-phospho-ttk-t676-antibody-ihc-testing-1.jpg)
Click image to see more details
Figure 1. Immunohistochemistry validation of TTK using Anti-Phospho-TTK (T676) Antibody (A01132T676).
Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100 (4°CProtein Target Info & Infographic
Gene/Protein Information For TTK (Source: Uniprot.org, NCBI)
Gene Name
TTK
Full Name
Dual specificity protein kinase TTK
Weight
97072 MW
Superfamily
protein kinase superfamily
Alternative Names
CT96; dual specificity protein kinase TTK; EC 2.7.12.1; ESK; FLJ38280; monopolar spindle 1-like 1; Mps1; MPS1L1; MPS1L1PYTcancer/testis antigen 96; phosphotyrosine picked threonine kinase; Phosphotyrosine picked threonine-protein kinase; PYT; TTK protein kinase; TTK TTK CT96, ESK, MPH1, MPS1, MPS1L1, PYT TTK protein kinase dual specificity protein kinase TTK|cancer/testis antigen 96|monopolar spindle 1 kinase|monopolar spindle 1-like 1|phosphotyrosine picked threonine kinase|phosphotyrosine picked threonine-protein kinase
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TTK, check out the TTK Infographic
![TTK infographic](/media/images/gene-infographic-example.jpg)
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TTK: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Phospho-TTK (T676) Antibody (A01132T676)
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No publications found for A01132T676
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