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Product Info Summary
| SKU: | A13680 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, ICC, WB |
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Product info
Product Name
Anti-Paralemmin3 PALM3 Antibody
View all Paralemmin 3 Antibodies
SKU/Catalog Number
A13680
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Paralemmin3 PALM3 Antibody (Catalog # A13680). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human.
Storage & Handling
Paralemmin3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Paralemmin3 PALM3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A13680)
Host
Rabbit
Contents
Paralemmin3 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Paralemmin3 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human Paralemmin3. The immunogen is located within amino acids 50 - 100 of Paralemmin3.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least two isoforms of Paralemmin3 are known to exist; this antibody will only detect the longer isoform
Reactive Species
A13680 is reactive to PALM3 in Human
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
71695 MW
Background of Paralemmin 3
Paralemmin3 is a recently identified protein that associates with the single immunoglobulin IL-1 receptor-related molecule (SIGIRR), a negative regulator of Toll-like receptor-interleukin 1 receptor signaling. Silencing of Paralemmin3 expression by RNAi inhibited the release of inflammatory cytokines in A549 cells after stimulation with lipopolysaccharide (LPS), suggesting Paralemmin3 may function as an adaptor in the LPS-TLR4 signaling pathway.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A13680 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Paralemmin3 antibody can be used for detection of Paralemmin3 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of Paralemmin3 in MCF7 cell lysate with Paralemmin3 antibody at 1 μg/mL.
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Immunocytochemistry of Paralemmin 3 in MCF7 cells with Paralemmin 3 antibody at 5 μg/mL.
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Immunofluorescence of Paralemmin 3 in MCF7 cells with Paralemmin 3 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For PALM3 (Source: Uniprot.org, NCBI)
Gene Name
PALM3
Full Name
Paralemmin-3
Weight
71695 MW
Superfamily
paralemmin family
Alternative Names
Paralemmin-3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PALM3, check out the PALM3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PALM3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Paralemmin3 PALM3 Antibody (A13680)
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