Anti-Otx2 Antibody Picoband®

Product Name

Anti-Otx2 Antibody Picoband®

View all OTX2 Antibodies

SKU/Catalog Number

PB9344

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Otx2 Antibody Picoband® catalog # PB9344. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Otx2 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9344)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human Otx2, identical to the related mouse sequence.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PB9344 is reactive to OTX2 in Human

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

32 kDa

Calculated molecular weight

31636 MW

Background of OTX2

OTX2 is also known as CPHD6 or MCOPS5. This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PB9344 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human

Positive Control

WB: COLO320 Whole Cell

Validation Images & Assay Conditions

Gene/Protein Information For OTX2 (Source: Uniprot.org, NCBI)

Alternative Names

Homeobox protein OTX2;Orthodenticle homolog 2;OTX2; OTX2 CPHD6, MCOPS5 orthodenticle homeobox 2 homeobox protein OTX2|orthodenticle homolog 2

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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