Homeobox protein OTX2 Antibodies

AND OTX2 ELISA kits, Homeobox protein OTX2 Proteins

Many biological assays use antibodies to detect Homeobox protein OTX2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Homeobox protein OTX2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Homeobox protein OTX2 antibodies...

We validate the specificity of these antibodies to Homeobox protein OTX2 by testing them on tissues known to express OTX2 positively and negatively. Browse below to find the OTX2 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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OTX2 Infographic by Boster Bio

All OTX2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Otx2 Antibody Picoband®

4 Q&As

Human

$370
Cat # PB9344
100 μg/vial

Anti-Homeobox protein OTX2 OTX2 Antibody

Human, Mouse, Rat

IF, IHC

$405
Cat # A02006
100ul

Anti-Homeobox protein OTX2 OTX2 Monoclonal Antibody

Human

ELISA, Flow Cytometry, IF, IHC, WB

$380
Cat # M02006
100ul

Anti-Otx2 Rabbit Monoclonal Antibody

Human

$370
Cat # M02006-1
100 μl/vial

OTX2 (NM_021728) Human Over-expression Lysate

Human

$628
Cat # LS005015
100 µg

OTX2 Overview

Facts about Homeobox protein OTX2.

OTX2 3D structure. Source: alphafold

Homeobox protein OTX2 (OTX2)

Transcription factor probably involved in the development of the brain and the sense organs. Can bind to the bicoid/BCD target sequence (BTS): 5'-TCTAATCCC-3'.

Gene Information

Human
Gene Name:	OTX2
Uniprot:	P32243
Entrez:	5015

Family

Belongs to:

paired homeobox family

Alternative Names

homeobox protein OTX2; MCOPS5; MGC45000; orthodenticle homeobox 2; orthodenticle homolog 2 (Drosophila); Orthodenticle homolog 2; Otx2

Molecular Weight

Mass (kDA):
31.636 kDA

Genomic Context


Human

Location:	14q22.3
Sequence:	14; NC_000014.9 (56799905..56810479, complement)

Subcellular Localizations

Nucleus.

Diseases

Nervousness
Microphthalmos
Pituitary Diseases
Anophthalmos
Neoplasms
Eye Abnormalities
Parkinson Disease
Medulloblastoma
Crest Syndrome
Hypoplasia
Congenital Abnormality
Brain Neoplasms

Chimera Disorder
Developmental Delay (disorder)
Retinal Diseases
Dwarfism
Hypopituitarism
Stenosis
Holoprosencephaly

Pathways

Gastrulation
Brain Development
Regionalization
Eye Development
Neurogenesis
Head Development
Localization
Cell Differentiation
Forebrain Development
Cell Proliferation
Cell Cycle
Brain Morphogenesis
Cell Fate Determination

Cell Death
Transdifferentiation
Pathogenesis
Midbrain Development
Methylation
Hindbrain Development
Translation

PTMs

Phosphorylation
Methylation
Cleavage

Acetylation
Reduction
Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/OTX2

References

PMID: 8101484 by Simeone A., et al. A vertebrate gene related to orthodenticle contains a homeodomain of the bicoid class and demarcates anterior neuroectoderm in the gastrulating mouse embryo.

PMID: 10372988 by Fong S.L., et al. Elements regulating the transcription of human interstitial retinoid- binding protein (IRBP) gene in cultured retinoblastoma cells.