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Product Info Summary
| SKU: | A12278 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-ORM1-like protein 1 ORMDL1 Antibody
SKU/Catalog Number
A12278
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-ORM1-like protein 1 ORMDL1 Antibody (Catalog # A12278). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
ORMDL1 antibody can be stored at 4 °C, stable for one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-ORM1-like protein 1 ORMDL1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12278)
Host
Rabbit
Contents
ORMDL1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
ORMDL1 antibody was raised against a 16 amino acid synthetic peptide of human ORMDL1. The immunogen is located within amino acids 50 - 100 of ORMDL1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
ORMDL1 antibody may cross-react with other ORMDL protein family members.
Reactive Species
A12278 is reactive to ORMDL1 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
17371 MW
Background of ORMDL1
The ORMDL (ORM1-like) family of proteins consist of ORMDL1, ORMDL2 and ORMDL3 that may play roles in gamma-secretase complex maturation. Localized to the membrane of the endoplasmic reticulum, ORMDLs are widely expressed and are implicated in the expression of Presenilin (PSI) which is involved in Alzheimer's disease (AD). Expression of ORMDL1 is down-regulated in PSI mutations, suggesting a possible role as a therapeutic target for AD. ORMDLs have recently been identified as a potential risk factor for childhood asthma.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A12278 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ORMDL1 antibody can be used for detection of ORMDL1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of ORMDL1 in SK-N-SH Cell lysate with ORMDL1 antibody at (A) 1 μg/mL and (B) 2 μg/mL.
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Immunohistochemistry of ORMDL1 in mouse brain tissue with ORMDL1 antibody at 5 μg/mL.
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Immunofluorescence of ORMDL1 in mouse brain tissue with ORMDL1 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For ORMDL1 (Source: Uniprot.org, NCBI)
Gene Name
ORMDL1
Full Name
ORM1-like protein 1
Weight
17371 MW
Superfamily
ORM family
Alternative Names
ORM1-like protein 1, Adoplin-1 ORMDL1 ORMDL sphingolipid biosynthesis regulator 1 ORM1-like protein 1|adoplin-1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ORMDL1, check out the ORMDL1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ORMDL1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ORM1-like protein 1 ORMDL1 Antibody (A12278)
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No publications found for A12278
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