Anti-Nuclear RNA export factor 1 NXF1 Antibody

Product Name

Anti-Nuclear RNA export factor 1 NXF1 Antibody

View all NXF1 Antibodies

SKU/Catalog Number

A02137

Size

100ul

Form

Liquid

Description

Boster Bio Anti-Nuclear RNA export factor 1 NXF1 Antibody catalog # A02137. Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Nuclear RNA export factor 1 NXF1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02137)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human CtBP1 around the phosphorylation site of S422.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A02137 is reactive to NXF1 in Human

Applications

A02137 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

70182 MW

Background of NXF1

Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) By similarity. Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.

Hateboer G., EMBO J. 14:3159-3169(1995).
Deloukas P., Nature 429:375-381(2004).
Matsuoka S., Science 316:1160-1166(2007).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:1000

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For NXF1 (Source: Uniprot.org, NCBI)

Alternative Names

DKFZp667O0311; Mex67; mRNA export factor TAP; nuclear RNA export factor 1; TAPMEX67; tip associating protein; Tip-associated protein; Tip-associating protein NXF1 MEX67, TAP nuclear RNA export factor 1 nuclear RNA export factor 1|mRNA export factor TAP|tip associating protein|tip-associated protein

For more info on NXF1, check out the NXF1 Infographic

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In this infographic, you will see the following information for NXF1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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