Product Info Summary
SKU: | A13234 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-NIPSNAP NIPSNAP1 Antibody
SKU/Catalog Number
A13234
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-NIPSNAP NIPSNAP1 Antibody (Catalog # A13234). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
NIPSNAP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-NIPSNAP NIPSNAP1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A13234)
Host
Rabbit
Contents
NIPSNAP Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
NIPSNAP antibody was raised against a 18 amino acid synthetic peptide from near the carboxy terminus of human NIPSNAP. The immunogen is located within the last 50 amino acids of NIPSNAP.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
This antibody is predicted to not cross-react with other members of the LRFN family.
Reactive Species
A13234 is reactive to NIPSNAP1 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
33310 MW
Background of NIPSNAP1
NIPSNAP is a member of an evolutionarily well conserved gene family and has a strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. Recent studies have indicated that NIPSNAP is involved in the regulation of the Ca2+-selective transient receptor potential vanilloid channel 6 (TRPV6). NIPSNAP1 associates with TRPV6 at the plasma membrane and inhibits TRPV6 currents. Other studies show that NIPSNAP's expression is reduced in the phenylketonuria (PKU) mouse brain, suggesting that NIPSNAP may play a role in memory.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A13234 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
NIPSNAP antibody can be used for the detection of NIPSNAP by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of NIPSNAP in human brain tissue lysate with NIPSNAP antibody at (A) 0.5 and (B) 1 μg/mL.
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Immunohistochemical staining of human brain tissue using Nipsnap antibody at 2.5 μg/mL.
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Immunofluorescence of NIPSNAP in Human Brain cells with NIPSNAP antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For NIPSNAP1 (Source: Uniprot.org, NCBI)
Gene Name
NIPSNAP1
Full Name
Protein NipSnap homolog 1
Weight
33310 MW
Superfamily
NipSnap family
Alternative Names
Protein NipSnap homolog 1, NipSnap1 NIPSNAP1 nipsnap homolog 1 protein NipSnap homolog 1|4-nitrophenylphosphatase domain and non-neuronal SNAP25-like 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on NIPSNAP1, check out the NIPSNAP1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for NIPSNAP1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-NIPSNAP NIPSNAP1 Antibody (A13234)
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