Anti-MYH6/7 Antibody

Product Name

Anti-MYH6/7 Antibody

View all MYH6 Antibodies

SKU/Catalog Number

A02808

Size

100ul

Form

Liquid

Description

Boster Bio Anti-MYH6/7 Antibody catalog # A02808. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-MYH6/7 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02808)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from Internal of human PIAS3.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A02808 is reactive to MYH6 in Human, Mouse, Rat

Applications

A02808 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

223735 MW

Background of MYH6

Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. Involved in regulating STAT3 signaling via inhibiting STAT3 DNA-binding and suppressing cell growth.

Jiang-Hong Man, Nucleic Acids Res., Nov 2006; 34: 5552 - 5566.
Amir Sonnenblick, Mol. Cell. Biol., Dec 2004; 24: 10584 - 10592.
Jianyin Long, PNAS, Jan 2004; 101: 99.
Hyun Duk Jang, J. Biol. Chem., Jun 2004; 279: 24873 - 24880.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:1000

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For MYH6 (Source: Uniprot.org, NCBI)

Alternative Names

alpha-MHC; ASD3; cardiomyopathy; CMD1EE; CMH14; Hypertrophic 1; MYH6; MYHC; MYHCA; MyHC-Alpha; Myosin Heavy Chain 6; Myosin Heavy Chain, Cardiac Muscle Alpha Isoform; Myosin, Heavy Chain 6, Cardiac Muscle, Alpha; Myosin, Heavy Polypeptide 6, Cardiac Muscle, Alpha (Cardiomyopathy, Hypertrophic 1); Myosin-6; SSS3 MYH6 ASD3, CMD1EE, CMH14, MYHC, MYHCA, SSS3, alpha-MHC myosin heavy chain 6 myosin-6|myHC-alpha|myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1)

For more info on MYH6, check out the MYH6 Infographic

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In this infographic, you will see the following information for MYH6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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