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Product Info Summary
| SKU: | A05448 |
|---|---|
| Size: | 100 µg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-MTAP Antibody
SKU/Catalog Number
A05448
Size
100 µg
Form
Liquid
Description
Boster Bio Anti-MTAP Antibody (Catalog# A05448). Tested in WB application(s). This antibody reacts with Human.
Storage & Handling
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Cite This Product
Anti-MTAP Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05448)
Host
Rabbit
Contents
100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A partial length recombinant MTAP protein (amino acids 50-270 )
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A05448 is reactive to MTAP in Human
Reconstitution
Calculated molecular weight
31236 MW
Background of MTAP
SmarcAL1 (SWI/SNF-related µatrix-associated actin-dependent regulator of chromatin a-like 1) is also known as HARP, HepA Related Protein, HHARP, SMARCA like Protein 1 and SWI/SNF Related. SmarcAL1 is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein shows sequence similarity to the E. coli RNA polymerase-binding protein HepA. Mutations in this gene are a cause of Schimke immunoosseous dysplasia (SIOD), an autosomal recessive disorder with the diagnostic features of spondyloepiphyseal dysplasia, renal dysfunction, and T-cell immunodeficiency.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A05448 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blot: 2-4 µg/ml
Validation Images & Assay Conditions
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Western blot analysis of MTAP. Anti-MTAP antibody was used at 2 &mu
Protein Target Info & Infographic
Gene/Protein Information For MTAP (Source: Uniprot.org, NCBI)
Gene Name
MTAP
Full Name
S-methyl-5'-thioadenosine phosphorylase
Weight
31236 MW
Superfamily
PNP/MTAP phosphorylase family
Alternative Names
S-methyl-5'-thioadenosine phosphorylase;2.4.2.28;5'-methylthioadenosine phosphorylase;MTA phosphorylase;MTAP;MTAPase;MTAP;MSAP; MTAP BDMF, DMSFH, DMSMFH, HEL-249, LGMBF, MSAP, c86fus methylthioadenosine phosphorylase S-methyl-5-thioadenosine phosphorylase|5-methylthioadenosine phosphorylase|MTA phosphorylase|MTAPase|MeSAdo phosphorylase|epididymis luminal protein 249|epididymis secretory sperm binding protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on MTAP, check out the MTAP Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for MTAP: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-MTAP Antibody (A05448)
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No publications found for A05448
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Customer Q&As
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1 Customer Q&As for Anti-MTAP Antibody
Question
We are currently using anti-MTAP antibody A05448 for human tissue, and we are satisfied with the WB results. The species of reactivity given in the datasheet says human. Is it true that the antibody can work on goat tissues as well?
Verified Customer
Verified customer
Asked: 2020-04-13
Answer
The anti-MTAP antibody (A05448) has not been validated for cross reactivity specifically with goat tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in goat you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2020-04-13
