Product Info Summary
SKU: | A03398 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-MMACHC Antibody
SKU/Catalog Number
A03398
Size
100ul
Form
Liquid
Description
Boster Bio Anti-MMACHC Antibody catalog # A03398. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-MMACHC Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03398)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human CSPG4 protein.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A03398 is reactive to MMACHC in Human, Mouse, Rat
Applications
A03398 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
31728 MW
Background of MMACHC
The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus.
Qian Wang, J. Virol., Jan 2004; 78: 821 - 833. RD Paladini,
RD Paladini, J. Cell Biol., Feb 1996; 132: 381.
M.K. Shamsher, Hum. Mol. Genet., Oct 1995; 4: 1875 - 1881.
Ying-Nai Wang, Mol. Pharmacol., Jan 2006; 69: 85 - 98.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-MMACHC Antibody A03398
Western blot analysis of extracts of various cell linesProtein Target Info & Infographic
Gene/Protein Information For MMACHC (Source: Uniprot.org, NCBI)
Gene Name
MMACHC
Full Name
Methylmalonic aciduria and homocystinuria type C protein
Weight
31728 MW
Superfamily
MMACHC family
Alternative Names
cblC; DKFZP564I122; FLJ25671; methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria; methylmalonic aciduria and homocystinuria type C protein; RP11-291L19.3 MMACHC cblC metabolism of cobalamin associated C cyanocobalamin reductase / alkylcobalamin dealkylase|alkylcobalamin:glutathione S-alkyltransferase|cyanocobalamin reductase (cyanide-eliminating)|methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria|methylmalonic aciduria and homocystinuria type C protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on MMACHC, check out the MMACHC Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for MMACHC: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-MMACHC Antibody (A03398)
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No publications found for A03398
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