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Product Info Summary
| SKU: | A03486 |
|---|---|
| Size: | 100μl |
| Reactive Species: | Human, Monkey, Mouse, Rat |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-MKP-2 DUSP4 Antibody
SKU/Catalog Number
A03486
Size
100μl
Form
Liquid
Description
Boster Bio Anti-MKP-2 DUSP4 Antibody catalog # A03486. Tested in WB applications. This antibody reacts with Human, Monkey, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-MKP-2 DUSP4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03486)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from the Internal region of human MKP-2. at AA rangle: 50-130
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A03486 is reactive to DUSP4 in Human, Monkey, Mouse, Rat
Applications
A03486 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
39 kDa
Calculated molecular weight
42953 MW
Background of DUSP4
The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
Kelian Chen, et,al. (2003) J. Cell Sci ; 117: 4527 - 4536.
Vera Strasser, et,al. (2004) Mol. Cell. Biol ; 24: 1378 - 1386.
Izhar Ben-Shlomo, et,al. (2003) Sci. STKE ; 2003: 9.
H. M. Kim, et,al. (2002) PNAS ; 99: 4020.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB, 1:500-1:2000
Validation Images & Assay Conditions
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Western Blot (WB) analysis of HepG2-UV cells using MKP-2 Polyclonal antibody.
Protein Target Info & Infographic
Gene/Protein Information For DUSP4 (Source: Uniprot.org, NCBI)
Gene Name
DUSP4
Full Name
Dual specificity protein phosphatase 4
Weight
42953 MW
Superfamily
protein-tyrosine phosphatase family
Alternative Names
dual specificity phosphatase 4; Dual specificity protein phosphatase hVH2; EC 3.1.3.16; EC 3.1.3.48; HVH2serine/threonine specific protein phosphatase; MAP kinase phosphatase 2; Mitogen-activated protein kinase phosphatase 2; MKP-2dual specificity protein phosphatase 4; MKP2VH1 homologous phosphatase 2; TYP; VH2 DUSP4 HVH2, MKP-2, MKP2, TYP dual specificity phosphatase 4 dual specificity protein phosphatase 4|MAP kinase phosphatase 2|VH1 homologous phosphatase 2|dual specificity protein phosphatase hVH2|mitogen-activated protein kinase phosphatase 2|serine/threonine specific protein phosphatase
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on DUSP4, check out the DUSP4 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for DUSP4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-MKP-2 DUSP4 Antibody (A03486)
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No publications found for A03486
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Customer Reviews
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Customer Q&As
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4 Customer Q&As for Anti-MKP-2 DUSP4 Antibody
Question
Would anti-MKP-2 antibody A03486 work for WB with testis?
Verified Customer
Verified customer
Asked: 2019-11-18
Answer
According to the expression profile of testis, DUSP4 is highly expressed in testis. So, it is likely that anti-MKP-2 antibody A03486 will work for WB with testis.
Boster Scientific Support
Answered: 2019-11-18
Question
Can you help my question with product A03486, anti-MKP-2 antibody. I was wondering if it would be possible to conjugate this antibody with biotin. I would need it to be without BSA or sodium azide. I am planning on using a buffer exchange of sodium azide with PBS only. Would there be problems for me to conjugate the antibody and store it in -20 degrees in small aliquots?
Verified Customer
Verified customer
Asked: 2019-08-21
Answer
We suggest not storing this antibody with PBS buffer only in -20 degrees. If you want to store it in -20 degrees it is best to add some cryoprotectant like glycerol. If you want carrier free A03486 anti-MKP-2 antibody, we can provide it to you in a special formula with trehalose and/or glycerol. These molecules will not interfere with conjugation chemistry and provide a good level of protection for the antibody from degradation. Please be sure to specify this in your purchase order.
Boster Scientific Support
Answered: 2019-08-21
Question
Would anti-MKP-2 antibody A03486 work on feline WB with testis?
E. Walker
Verified customer
Asked: 2019-02-04
Answer
Our lab technicians have not validated anti-MKP-2 antibody A03486 on feline. You can run a BLAST between feline and the immunogen sequence of anti-MKP-2 antibody A03486 to see if they may cross-react. If the sequence homology is close, then you can perform a pilot test. Keep in mind that since we have not validated feline samples, this use of the antibody is not covered by our guarantee. However we have an innovator award program that if you test this antibody and show it works in feline testis in WB, you can get your next antibody for free.
Boster Scientific Support
Answered: 2019-02-04
Question
I was wanting to use to test anti-MKP-2 antibody A03486 on monkey testis for research purposes, then I may be interested in using anti-MKP-2 antibody A03486 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?
Verified Customer
Verified customer
Asked: 2017-05-23
Answer
The products we sell, including anti-MKP-2 antibody A03486, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.
Boster Scientific Support
Answered: 2017-05-23
