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Product Info Summary
| SKU: | A17310 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IHC-P, WB |
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Product info
Product Name
Anti-MettL7B Antibody
SKU/Catalog Number
A17310
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-MettL7B Antibody (Catalog # A17310). Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
MettL7B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-MettL7B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A17310)
Host
Rabbit
Contents
MettL7B Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
MettL7B antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human MettL7B. The immunogen is located within the last 50 amino acids of MettL7B.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
This MettL7B antibody is predicted to not cross-react with MettL7A.
Reactive Species
A17310 is reactive to METTL7B in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
27775 MW
Background of Mettl7b
MettL7B belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A17310 is guaranteed for ELISA, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
MettL7B antibody can be used for detection of Mettl7B by Western blot at 2 - 4 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL.
Antibody validated: Western Blot in rat samples and Immunohistochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of MettL7B in rat spleen tissue lysate with MettL7B antibody at (A) 2 and (B) 4 μg/mL.
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Immunohistochemistry of Mett7LB in human spleen tissue with MettL7B antibody at 2.5 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For METTL7B (Source: Uniprot.org, NCBI)
Gene Name
METTL7B
Full Name
Methyltransferase-like protein 7B
Weight
27775 MW
Superfamily
methyltransferase superfamily
Alternative Names
ALDI, Methyltransferase-like protein 7B
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on METTL7B, check out the METTL7B Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for METTL7B: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-MettL7B Antibody (A17310)
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