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Product Info Summary
| SKU: | A11860 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-LYR motif-containing protein 1 LYRM1 Antibody
SKU/Catalog Number
A11860
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-LYR motif-containing protein 1 LYRM1 Antibody (Catalog # A11860). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
LYRM1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-LYR motif-containing protein 1 LYRM1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A11860)
Host
Rabbit
Contents
LYRM1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
LYRM1 antibody was raised against a 17 amino acid synthetic peptide near the center of human LYRM1. The immunogen is located within the first 50 amino acids of LYRM1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
KPNA7 antibody is human specific. KPNA7 antibody is predicted to not cross-react with other Importin alpha family members.
Reactive Species
A11860 is reactive to LYRM1 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
14282 MW
Background of LYRM1
LYRM1 was one of many genes identified through a suppression subtractive hybridization comparing their expression in omental adipose tissue of obese patients compared to non-obese individuals. Further study confirms that both mRNA and protein levels of LYRM1 are higher in obese individuals. LYRM1 is widely expressed, with highest levels occurring in adipose and liver tissues. It is thought that LYRM1 promotes preadipocyte proliferation and can inhibit apoptosis of preadipocytes. Ectopic LYRM1 expression did not significantly affect adipogenesis, suggesting that LYRM1 can influence adipose tissue homeostasis by modulating the size of the preadipocyte pool.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A11860 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
LYRM1 antibody can be used for detection of LYRM1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of LYRM1 in human liver tissue lysate with LYRM1 antibody at (A) 1 and (B) 2 μg/mL.
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Immunohistochemistry of LYRM1 in rat liver tissue with LYRM1 antibody at 5 μg/mL.
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Immunofluorescence of LYRM1 in rat liver tissue with LYRM1 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For LYRM1 (Source: Uniprot.org, NCBI)
Gene Name
LYRM1
Full Name
LYR motif-containing protein 1
Weight
14282 MW
Superfamily
complex I LYR family
Alternative Names
A211C6.1, LYR motif-containing protein 1 LYRM1 A211C6.1 LYR motif containing 1 LYR motif-containing protein 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on LYRM1, check out the LYRM1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for LYRM1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-LYR motif-containing protein 1 LYRM1 Antibody (A11860)
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