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Product Info Summary
| SKU: | M01120 |
|---|---|
| Size: | 100ug/vial |
| Reactive Species: | Human |
| Host: | Mouse |
| Application: | IHC |
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Product info
Product Name
Anti-Luteinizing Hormone / Choriogonadotropin Receptor (LHCGR) Monoclonal Antibody
SKU/Catalog Number
M01120
Size
100ug/vial
Form
Liquid
Description
Boster Bio Anti-Luteinizing Hormone / Choriogonadotropin Receptor (LHCGR) Monoclonal Antibody (Catalog # M01120). Tested in IHC applications. This antibody reacts with Human.
Storage & Handling
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Cite This Product
Anti-Luteinizing Hormone / Choriogonadotropin Receptor (LHCGR) Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01120)
Host
Mouse
Contents
Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Clonality
Monoclonal
Clone Number
Clone: LHCGR/1417
Isotype
IgG1, kappa
Immunogen
Recombinant fragment (around aa 70-410) of human LHCGR protein (exact sequence is proprietary)
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Does not cross-react with primate, avian or amphibian GR.
Reactive Species
M01120 is reactive to LHCGR in Human
Reconstitution
Reconstitute with distilled water.
Observed Molecular Weight
68 kDa
Calculated molecular weight
78643 MW
Background of LHR
Recognizes a protein of 78-85kDa, which is identified as Luteinizing hormone / choriogonadotropin receptor. Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone / choriogonadotropin receptor (LHCGR) as a seven transmembrane, G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M01120 is guaranteed for IHC Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.
Validation Images & Assay Conditions
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SDS-PAGE analysis purified Anti-LHCGR Mouse Monoclonal Antibody (LHCGR/1417). Confirmation of integrity and purity of antibody.
Protein Target Info & Infographic
Gene/Protein Information For LHCGR (Source: Uniprot.org, NCBI)
Gene Name
LHCGR
Full Name
Lutropin-choriogonadotropic hormone receptor
Weight
78643 MW
Superfamily
G-protein coupled receptor 1 family
Alternative Names
Lutropin-choriogonadotropic hormone receptor;LH/CG-R;Luteinizing hormone receptor;LHR;LSH-R;LHCGR;LCGR, LGR2, LHRHR; LHCGR HHG, LCGR, LGR2, LH/CG-R, LH/CGR, LHR, LHRHR, LSH-R, ULG5 luteinizing hormone/choriogonadotropin receptor lutropin-choriogonadotropic hormone receptor|hypergonadotropic hypogonadism|lutropin/choriogonadotropin receptor
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on LHCGR, check out the LHCGR Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for LHCGR: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Luteinizing Hormone / Choriogonadotropin Receptor (LHCGR) Monoclonal Antibody (M01120)
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No publications found for M01120
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