Anti-LST1 Purified Monoclonal Antibody

Product Name

Anti-LST1 Purified Monoclonal Antibody

View all LST1 Antibodies

SKU/Catalog Number

M03702

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-LST1 Purified Monoclonal Antibody (Catalog# M03702). Tested in IP, WB, ICC application(s). This antibody reacts with Human.

Storage & Handling

Store at 2-8°C. Do not freeze.

Cite This Product

Anti-LST1 Purified Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M03702)

Host

Mouse

Contents

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Clonality

Monoclonal

Clone Number

LST1/02

Isotype

Mouse IgG1

Immunogen

KLH-fused peptide corresponding to amino acids SSEGPDLRGRDKRGT of human LST1. The antibody LST1/02 reacts with an extracellular epitope of LST1, an approximately 6-11 kDa protein expressed as various transmembrane or soluble forms. LST1 is found predominantly on monocytes and dendritic cells. It migrates on SDS PAGE gels as approximately 25-28 kDa molecule.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

This antibody does not cross-react with Thy-1.1 alloantigen.

Reactive Species

M03702 is reactive to LST1 in Human

Reconstitution

Observed Molecular Weight

42 kDa

Calculated molecular weight

10792 MW

Background of LST1

LST1 (leukocyte-specific transcript 1, also known as B144) is expressed in cells of myeloid/erythroid lineage (monocytes, granulocytes, dendritic cells, platelets, erythrocytes). At least 14 alternatively spliced variants (LST1/A –; LST1/N) can be detected; some of them (LST1/A, B, C, G, I, K) are transmembrane cell surface-exposed forms, the other are soluble. LST1 induces production of long, thin filopodia in dendritic cells, has an inhibitory effect on lymphocyte proliferation and may have an immunomodulatory role. LST1/A is an 11 kDa transmembrane adaptor present in membrane rafts and forms spontaneously covalent homodimers. Its intracellular domain contains two tyrosine motifs, one of them being an ITIM very similar to such motifs in Siglec.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

M03702 is guaranteed for IP, ICC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunoprecipitation: Positive control: RAJI human Burkitt lymphoma cell line.
Western blotting: The antigen migrates on SDS PAGE gels as approximately 25-28 kDa molecule.

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For LST1 (Source: Uniprot.org, NCBI)

Alternative Names

LST-1, B144 LST1 B144, D6S49E, LST-1 leukocyte specific transcript 1 leukocyte-specific transcript 1 protein|lymphocyte 117

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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