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Product Info Summary
| SKU: | A12062 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-LRFN4 Antibody
View all SALM3/LRFN4 Antibodies
SKU/Catalog Number
A12062
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-LRFN4 Antibody (Catalog # A12062). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
LRFN4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-LRFN4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12062)
Host
Rabbit
Contents
LRFN4 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
LRFN4 antibody was raised against a 14amino acid synthetic peptide near the carboxy terminus of human LRFN4. The immunogen is located within amino acids 550 - 600 of LRFN4.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
This antibody is predicted to not cross-react with other members of the LRFN family.
Reactive Species
A12062 is reactive to LRFN4 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
66860 MW
Background of SALM3/LRFN4
LRFN4 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system. At least two isoforms of LRFN4 are known to exist.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A12062 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
LRFN4 antibody can be used for detection of LRFN4 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of LRFN4 in rat brain lysate with LRFN4 antibody at 1 μg/mL.
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Immunohistochemistry of LRFN4 in mouse brain tissue with LRFN4 antibody at 2.5 μg/mL.
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Immunofluorescence of LRFN4 in mouse brain tissue with LRFN4 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For LRFN4 (Source: Uniprot.org, NCBI)
Gene Name
LRFN4
Full Name
Leucine-rich repeat and fibronectin type-III domain-containing protein 4
Weight
66860 MW
Superfamily
LRFN family
Alternative Names
SALM3, SALM3., FIGLER6, SALM3, Leucine-rich repeat and fibronectin type-III domain-containing protein 4 LRFN4 FIGLER6, SALM3, SALM3. leucine rich repeat and fibronectin type III domain containing 4 leucine-rich repeat and fibronectin type-III domain-containing protein 4|fibronectin type III, immunoglobulin and leucine rich repeat domains 6
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on LRFN4, check out the LRFN4 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for LRFN4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-LRFN4 Antibody (A12062)
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