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Product Info Summary
| SKU: | A11623 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-LRFN2 Antibody
SKU/Catalog Number
A11623
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-LRFN2 Antibody (Catalog # A11623). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
LRFN2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-LRFN2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A11623)
Host
Rabbit
Contents
LRFN2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
LRFN2 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human LRFN2. The immunogen is located within amino acids 700 - 750 of LRFN2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least two isoforms of LRFN2 are known to exist. This antibody is predicted to not cross-react with other members of the LRFN family.
Reactive Species
A11623 is reactive to LRFN2 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
84731 MW
Background of LRFN2
LRFN2 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A11623 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
LRFN2 antibody can be used for detection of LRFN2 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse and rat samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of LRFN2 in rat brain lysate with LRFN2 antibody at (A) 1 and (B) 2 μg/mL.
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Immunohistochemistry of LRFN2 in mouse brain tissue with LRFN2 antibody at 2.5 μg/mL.
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Immunofluorescence of LRFN2 in mouse brain tissue with LRFN2 antibody at 20 μg/mL.
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Western blot analysis of LRFN2 expression in mouse brain tissue lysate with LRFN2 antibody at 1 μg/ml.
Protein Target Info & Infographic
Gene/Protein Information For LRFN2 (Source: Uniprot.org, NCBI)
Gene Name
LRFN2
Full Name
Leucine-rich repeat and fibronectin type-III domain-containing protein 2
Weight
84731 MW
Superfamily
LRFN family
Alternative Names
SALM1, FIGLER2, KIAA1246, SALM1, Leucine-rich repeat and fibronectin type-III domain-containing protein 2, Synaptic adhesion-like molecule 1 LRFN2 FIGLER2, KIAA1246, SALM1 leucine rich repeat and fibronectin type III domain containing 2 leucine-rich repeat and fibronectin type-III domain-containing protein 2|fibronectin type III, immunoglobulin and leucine rich repeat domains 2|synaptic adhesion-like molecule 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on LRFN2, check out the LRFN2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for LRFN2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-LRFN2 Antibody (A11623)
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