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Product Info Summary
| SKU: | A03296 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-LMX1B Antibody
SKU/Catalog Number
A03296
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-LMX1B Antibody (Catalog # A03296). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
LMX1B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-LMX1B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03296)
Host
Rabbit
Contents
LMX1B Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Rabbit polyclonal LMX1B antibody was raised against a 17 amino acid peptide near the carboxy terminus of human LMX1B. The immunogen is located within amino acids 280 - 330 of LMX1B.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least three isoforms are known to exist. This antibody is predicted to not cross-react with LMX1A.
Reactive Species
A03296 is reactive to LMX1B in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
44917 MW
Background of LMX1B
The LIM homeobox transcription factor 1B (LMX1B) belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1B regulates mid-hindbrain patterning; LMX1B-null mice embryos have a severe reduction in the number of midbrain dopaminergic neurons compared to wild-type. While LMX1B appears to be important for both the development and the survival of dopamine neurons, the related LMX1A is crucial for the differentiation of these cells. However, LMX1A and LMX1B function cooperatively to regulated the proliferation, specification and differentiation of midbrain dopaminergic neuronal progenitors.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A03296 is guaranteed for ELISA, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
LMX1B antibody can be used for detection of LMX1B by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of LMX1B in A-20 cell lysate with LMX1B antibody at (A) 1 and (B) 2 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For LMX1B (Source: Uniprot.org, NCBI)
Gene Name
LMX1B
Full Name
LIM homeobox transcription factor 1-beta
Weight
44917 MW
Alternative Names
NPS1, LMX1.2, LIM homeobox transcription factor 1-beta LMX1B FSGS10, LMX1.2, NPS1 LIM homeobox transcription factor 1 beta LIM homeobox transcription factor 1-beta|LIM/homeobox protein 1.2|LMX-1.2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on LMX1B, check out the LMX1B Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for LMX1B: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-LMX1B Antibody (A03296)
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No publications found for A03296
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