Anti-LMCD1 Antibody (C-term)

Product Name

Anti-LMCD1 Antibody (C-term)

View all LMCD1 Antibodies

SKU/Catalog Number

A08888

Size

80 µl

Description

Boster Bio Anti-LMCD1 Antibody (C-term) (Catalog # A08888). Tested in WB application(s). This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Cite This Product

Anti-LMCD1 Antibody (C-term) (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08888)

Host

Rabbit

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

This LMCD1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 316-350 amino acids from the C-terminal region of human LMCD1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A08888 is reactive to LMCD1 in Human, Mouse, Rat

Reconstitution

Observed Molecular Weight

Calculated molecular weight

40833 Da

Background of LMCD1

Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue- specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity). Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A08888 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:1000

Positive Control

Validation Images & Assay Conditions

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Western blot analysis of lysates from human skeletal muscle, mouse lung, rat lung tissue lysate (from left to right), using LMCD1 Antibody (C-term). A08888 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.

Gene/Protein Information For LMCD1 (Source: Uniprot.org, NCBI)

Alternative Names

dyxin; LIM and cysteine-rich domains 1; LIM and cysteine-rich domains protein 1 LMCD1 LIM and cysteine rich domains 1 LIM and cysteine-rich domains protein 1|dyxin

For more info on LMCD1, check out the LMCD1 Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for LMCD1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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