Anti-LAL LIPA Monoclonal Antibody

Product Name

Anti-LAL LIPA Monoclonal Antibody

View all Lipase A Antibodies

SKU/Catalog Number

A03895

Size

100μl

Form

Liquid

Description

Boster Bio Anti-LAL LIPA Monoclonal Antibody catalog # A03895. Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-LAL LIPA Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03895)

Host

Mouse

Contents

Purified antibody in PBS containing 0.03% sodium azide.

Clonality

Monoclonal

Clone Number

9G7F12; 7G6D7

Isotype

IgG2a

Immunogen

Purified recombinant fragment of LAL expressed in E. Coli.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A03895 is reactive to LIPA in Human

Applications

A03895 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

39 kDa

Calculated molecular weight

45419 MW

Background of Lipase A

Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.

Chong J.A.et.al. (1995)Cell 80:949-957
Schoenherr C.J.et.al.(1995)Science 267:1360-1363
Scholl T.et.al.(1996)J. Immunol. 156:1448-1457
Lunyak V.V.et.al. (2002)Science 298:1747-1752

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000

Validation Images & Assay Conditions

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Western Blot (WB) analysis using LAL Monoclonal antibody against LAL recombinant protein.

Gene/Protein Information For LIPA (Source: Uniprot.org, NCBI)

Alternative Names

Acid cholesteryl ester hydrolase; CESD; Cholesteryl esterase; EC 3.1.1; EC 3.1.1.13; LALCESDcholesterol ester hydrolase; LIPA; Lipase A; lipase A, lysosomal acid, cholesterol esterase; lysosomal acid lipase; lysosomal acid lipase/cholesteryl ester hydrolase; Sterol esterase LIPA CESD, LAL lipase A, lysosomal acid type lysosomal acid lipase/cholesteryl ester hydrolase|acid cholesteryl ester hydrolase|cholesterol ester hydrolase|cholesteryl esterase|lipase A, lysosomal acid, cholesterol esterase|lysosomal acid lipase|sterol esterase

For more info on LIPA, check out the LIPA Infographic

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In this infographic, you will see the following information for LIPA: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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