Anti-Kv1.1 potassium channel/KCNA1 Antibody Picoband®

Product Name

Anti-Kv1.1 potassium channel/KCNA1 Antibody Picoband®

View all Kv1.1 Antibodies

SKU/Catalog Number

PA2296

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Kv1.1 potassium channel/KCNA1 Antibody catalog # PA2296. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Kv1.1 potassium channel/KCNA1 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2296)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human Kv1.1 potassium channel, different from the related mouse sequence by two amino acids, and from the related rat sequence by four amino acids .

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA2296 is reactive to KCNA1 in Human, Mouse, Rat

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

56 kDa

Calculated molecular weight

56466 MW

Background of Kv1.1

Potassium voltage-gated channel subfamily A member 1, also known as Kv1.1, is a shaker related voltage-gated potassium channel that in humans is encoded by the KCNA1 gene. It is mapped to 12p13.32. The protein functions as a potassium selective channel through which the potassium ion may pass through in consensus with the electrochemical gradient. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PA2296 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat

Positive Control

WB: Rat Brain Tissue, Rat Testis Tissue, Rat Cardiac Muscle Tissue, HELA Whole Cell, U87 Whole Cell, SHG Whole Cell, NEURO Whole Cell

Validation Images & Assay Conditions

Gene/Protein Information For KCNA1 (Source: Uniprot.org, NCBI)

Alternative Names

Potassium voltage-gated channel subfamily A member 1;Voltage-gated K (+) channel HuKI ;Voltage-gated potassium channel HBK1 ;Voltage-gated potassium channel subunit Kv1.1;KCNA1; KCNA1 AEMK, EA1, HBK1, HUK1, KV1.1, MBK1, MK1, RBK1 potassium voltage-gated channel subfamily A member 1 potassium voltage-gated channel subfamily A member 1|potassium channel, voltage gated shaker related subfamily A, member 1|potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)|voltage-gated K(+) channel HuKI|voltage-gated potassium channel HBK1|voltage-gated potassium channel subunit Kv1.1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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