Anti-KLRA3 Antibody

Product Name

Anti-KLRA3 Antibody

View all Klra3 Antibodies

SKU/Catalog Number

A33575

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-KLRA3 Antibody (Catalog # A33575). Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat.

Storage & Handling

KLRA3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-KLRA3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A33575)

Host

Rabbit

Contents

KLRA3 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

KLRA3 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of mouse KLRA3. The immunogen is located within the last 50 amino acids of KLRA3.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

This antibody may cross-react with other LY49 receptors.

Reactive Species

A33575 is reactive to KLRA3 in Mouse, Rat

Reconstitution

Observed Molecular Weight

68 kDa

Calculated molecular weight

31311 MW

Background of Klra3

KLRA3 (also known as Ly49C) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA3 is thought to be an inhibitory receptor, recognizing peptide -receptive H-2Kb.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A33575 is guaranteed for ELISA, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

KLRA3 antibody can be used for detection of KLRA3 by Western blot at 2 μg/mL.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For KLRA3 (Source: Uniprot.org, NCBI)

Alternative Names

5E6, Nk2, Nk-2, Ly49c, Nk2.1, NK-2.1, Ly-49c, Ly49C, Killer cell lectin-like receptor 3, 5E6 Klra3|5E6, Ly49, Ly49c, NK-2., NK-2.1, Nk, Nk-, Nk-2, Nk2, Nk2., Nk2.1|killer cell lectin-like receptor, subfamily A, member 3|killer cell lectin-like receptor 3|T-cell surface glycoprotein Ly-49C|lymphocyte 49c|natural killer cell-associated 2

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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