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Product Info Summary
| SKU: | A33575 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-KLRA3 Antibody
SKU/Catalog Number
A33575
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-KLRA3 Antibody (Catalog # A33575). Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat.
Storage & Handling
KLRA3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-KLRA3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A33575)
Host
Rabbit
Contents
KLRA3 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
KLRA3 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of mouse KLRA3. The immunogen is located within the last 50 amino acids of KLRA3.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
This antibody may cross-react with other LY49 receptors.
Reactive Species
A33575 is reactive to Klra3 in Mouse, Rat
Applications
A33575 is guaranteed for ELISA, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
31311 MW
Background of Klra3
KLRA3 (also known as Ly49C) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA3 is thought to be an inhibitory receptor, recognizing peptide -receptive H-2Kb.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
KLRA3 antibody can be used for detection of KLRA3 by Western blot at 2 μg/mL.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of KLRA3 in mouse brain tissue lysate with KLRA3 antibody at 2 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For Klra3 (Source: Uniprot.org, NCBI)
Gene Name
Klra3
Full Name
Killer cell lectin-like receptor 3
Weight
31311 MW
Alternative Names
5E6; Klra3 killer cell lectin-like receptor, subfamily A, member 3 ; Ly49c; Nk2; Nk-2; Nk2.1; NK-2.1 Klra3|5E6, Ly49, Ly49c, NK-2., NK-2.1, Nk, Nk-, Nk-2, Nk2, Nk2., Nk2.1|killer cell lectin-like receptor, subfamily A, member 3|killer cell lectin-like receptor 3|T-cell surface glycoprotein Ly-49C|lymphocyte antigen 49c|natural killer cell-associated antigen 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Klra3, check out the Klra3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Klra3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-KLRA3 Antibody (A33575)
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