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Product Info Summary
| SKU: | A33282 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-KLRA2 Antibody
SKU/Catalog Number
A33282
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-KLRA2 Antibody (Catalog # A33282). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Mouse, Rat.
Storage & Handling
KLRA2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-KLRA2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A33282)
Host
Rabbit
Contents
KLRA2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
KLRA2 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of mouse KLRA2. The immunogen is located within the last 50 amino acids of KLRA2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least two isoforms of HDGFRP2 are known to exist; this antibody will recognize both isoforms. This antibody is predicted to not cross-react with other HDGFRP family members
Reactive Species
A33282 is reactive to KLRA2 in Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
33607 MW
Background of Klra2
KLRA2 (also known as Ly49B) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA2 is thought to be an inhibitory receptor and associates with the protein tyrosine phosphatases SHP1, SHP2, and SHIP in transfected cells. This antibody is predicted to not cross-react with other LY49 receptors.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A33282 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
KLRA2 antibody can be used for detection of KLRA2 by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of KLRA2 in mouse spleen tissue lysate with KLRA2 antibody at (A) 0.5 and (B) 1 μg/mL.
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Immunohistochemistry of KLRA2 in mouse spleen tissue with KLRA2 antibody at 2.5 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For KLRA2 (Source: Uniprot.org, NCBI)
Gene Name
KLRA2
Full Name
Killer cell lectin-like receptor 2
Weight
33607 MW
Alternative Names
Ly49b, Klra30, Ly49-b, Ly49b, Killer cell lectin-like receptor 2, Lymphocyte antigen 49b, Ly-49b Klra2|Klra30, Ly49, Ly49b|killer cell lectin-like receptor, subfamily A, member 2|killer cell lectin-like receptor 2|NK cell inhibitory receptor Klra2|T-cell surface glycoprotein Ly-49B|T-cell surface glycoprotein Ly49b|killer cell lectin-like receptor subfamily A member 30|ly-49b|lymphocyte 49b|membrane protein Ly49b
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on KLRA2, check out the KLRA2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for KLRA2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-KLRA2 Antibody (A33282)
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