Click image to see more details
Product Info Summary
| SKU: | A03789 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, ICC, WB |
Customers Who Bought This Also Bought
Product info
Product Name
Anti-KIR2DS2 Antibody
SKU/Catalog Number
A03789
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-KIR2DS2 Antibody (Catalog # A03789). Tested in ELISA, WB, IF, ICC applications. This antibody reacts with Human.
Storage & Handling
KIR2DS2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-KIR2DS2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03789)
Host
Rabbit
Contents
KIR2DS2 antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
KIR2DS2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human KIR2DS2. The immunogen is located within the last 50 amino acids of KIR2DS2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
KIR2DS2 antibody is human specific. Multiple isoforms are known to exist.
Reactive Species
A03789 is reactive to KIR2DS2 in Human
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
33502 MW
Background of KIR2DS2
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells (1). The KIR proteins are classified by the number of extracellular immunoglobulin domains and by whether they have a long (L) or short (S) cytoplasmic domain (2,3). KIR proteins are thought to play an important role in regulation of the immune response (3). KIR2DS2 downregulates the cytotoxicity of NK cells upon recognition of specific class I major histocompatibility complex (MHC) molecules on target cells and is a receptor on natural killer (NK) cells for HLA-C alleles (3,4).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A03789 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
KIR2DS2 antibody can be used for detection of KIR2DS2 by Western blot at 1 - 2 μg/ml. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of KIR2DS2 in 293 cell lysate with KIR2DS2 antibody at (A) 1 and (B) 2 μg/ml.
Click image to see more details
Immunocytochemistry of KIR2DS2 in Hek293 cells with KIR2DS2 antibody at 5 μg/mL.
Click image to see more details
Immunofluorescence of KIR2DS2 in 293 cells with KIR2DS2 antibody at 20 μg/ml.
Click image to see more details
Immunofluorescence of KIR2DS2 in Hek293 cells with KIR2DS2 antibody at 20 μg/mL.
Green: KIR2DS2 Antibody (A03789)
Blue: DAPI staining
Protein Target Info & Infographic
Gene/Protein Information For KIR2DS2 (Source: Uniprot.org, NCBI)
Gene Name
KIR2DS2
Full Name
Killer cell immunoglobulin-like receptor 2DS2
Weight
33502 MW
Superfamily
immunoglobulin superfamily
Alternative Names
Killer cell immunoglobulin-like receptor two domains short cytoplasmic tail 2, KIR2DL3, MHC class I NK cell receptor, Natural killer-associated transcript 5, NKAT5, p58 KIR, p58 natural killer cell receptor clone CL-49, p58 NK receptor KIR2DS2 183ActI, CD158J, CD158b, KIR-2DS2, KIR2DL1, NKAT-5, NKAT5, cl-49 killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2 killer cell immunoglobulin-like receptor 2DS2|CD158 -like family member J|KIR2DS2 Killer-cell Immunoglobulin-like Receptor|MHC class I NK cell receptor|NK receptor 183 ActI|killer cell immunoglobulin-like receptor KIR2DS2|killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2|killer-cell Ig-like receptor|killer-cell immunoglobulin-like receptor two domains short tail 2 protein|natural killer associated transcript 5|natural killer cell inhibitory receptor|p58 killer cell inhibitory receptor KIR-K7a|p58 natural killer cell receptor clone CL-49
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on KIR2DS2, check out the KIR2DS2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for KIR2DS2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-KIR2DS2 Antibody (A03789)
Hello CJ!
No publications found for A03789
*Do you have publications using this product? Share with us and receive a reward. Ask us for more details.
Recommended Resources
Here are featured tools and databases that you might find useful.
- Boster's Pathways Library
- Protein Databases
- Bioscience Research Protocol Resources
- Data Processing & Analysis Software
- Photo Editing Software
- Scientific Literature Resources
- Research Paper Management Tools
- Molecular Biology Software
- Primer Design Tools
- Bioinformatics Tools
- Phylogenetic Tree Analysis
Customer Reviews
Have you used Anti-KIR2DS2 Antibody?
Submit a review and receive an Amazon gift card.
- $30 for a review with an image
0 Reviews For Anti-KIR2DS2 Antibody
Customer Q&As
Have a question?
Find answers in Q&As, reviews.
Can't find your answer?
Submit your question
