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Product Info Summary
| SKU: | M08181 |
|---|---|
| Size: | 80 µl |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-KCNMB2 Antibody (N-term)
SKU/Catalog Number
M08181
Size
80 µl
Description
Boster Bio Anti-KCNMB2 Antibody (N-term) (Catalog # M08181). Tested in WB application(s). This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Cite This Product
Anti-KCNMB2 Antibody (N-term) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M08181)
Host
Rabbit
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
This KCNMB2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 32-66 amino acids from the N-terminal region of human KCNMB2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M08181 is reactive to KCNMB2 in Human, Mouse, Rat
Reconstitution
Calculated molecular weight
27130 Da
Background of KCNMB2
Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex. May participate in KCNMA1 inactivation in chromaffin cells of the adrenal gland or in hippocampal CA1 neurons.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M08181 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:2000
Validation Images & Assay Conditions
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All lanes : Anti-KCNMB2 Antibody (N-term) at 1:2000 dilution
Lane 1: human brain lysates
Lane 2: human heart lysates
Lane 3: human kidney lysates
Lane 4: HepG2 whole cell lysates
Lane 5: mouse brain lysates
Lane 6: rat brain lysates
Lysates/proteins at 20 µg per lane.
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution
Predicted band size : 27 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.
Protein Target Info & Infographic
Gene/Protein Information For KCNMB2 (Source: Uniprot.org, NCBI)
Gene Name
KCNMB2
Full Name
Calcium-activated potassium channel subunit beta-2
Weight
27130 Da
Superfamily
KCNMB (TC 8.A.14.1) family
Alternative Names
Calcium-activated potassium channel subunit beta-2, BK channel subunit beta-2, BKbeta2, Hbeta2, Calcium-activated potassium channel, subfamily M subunit beta-2, Charybdotoxin receptor subunit beta-2, Hbeta3, K(VCA)beta-2, Maxi K channel subunit beta-2, Slo-beta-2, KCNMB2 KCNMB2 potassium calcium-activated channel subfamily M regulatory beta subunit 2 calcium-activated potassium channel subunit beta-2|BK channel beta subunit 2|BK channel subunit beta-2|MaxiK channel beta 2 subunit|MaxiK channel beta-subunit 2|big potassium channel beta subunit 2|charybdotoxin receptor subunit beta-2|hCG1646471|hbeta2|k(VCA)beta-2|large conductance calcium-activated potassium channel beta 2 subunit|large-conductance Ca2+-activated K+ channel beta2 subunit|potassium channel subfamily M regulatory beta subunit 2|potassium large conductance calcium-activated channel, subfamily M, beta member 2|slo-beta-2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on KCNMB2, check out the KCNMB2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for KCNMB2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-KCNMB2 Antibody (N-term) (M08181)
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