Product Info Summary
SKU: | A11947 |
---|---|
Size: | 100 µl |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-KCNH3/Kv12.2 Antibody
SKU/Catalog Number
A11947
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-KCNH3/Kv12.2 Antibody (Catalog # A11947). Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-KCNH3/Kv12.2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A11947)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from Internal of human KCNH3.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A11947 is reactive to Kcnh3 in Human, Mouse, Rat
Applications
A11947 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
117129 MW
Background of Kv12.2
Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits an outward current with fast inactivation. Channel properties may be modulated by cAMP and subunit assembly.
Miyake A., J. Biol. Chem. 274:25018-25025(1999).
Nagase T., DNA Res. 6:337-345(1999).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blotting: 1:500~1:3000
Validation Images & Assay Conditions
![a11947 western blotting analysis 1 a11947 western blotting analysis 1](https://www.bosterbio.com/media/catalog/product/a/1/a11947-western-blotting-analysis-1.jpg)
Click image to see more details
Western blot analysis of extracts from HeLa cells, using KCNH3 antibody A11947.
Protein Target Info & Infographic
Gene/Protein Information For Kcnh3 (Source: Uniprot.org, NCBI)
Gene Name
Kcnh3
Full Name
Potassium voltage-gated channel subfamily H member 3
Weight
117129 MW
Superfamily
potassium channel family
Alternative Names
BEC1; brain-specific eag-like channel 1; ELK channel 2; ELK2; ether-a-go-go K(+) channel family member; ether-a-go-go-like potassium channel 2; KIAA1282; Kv12.2; potassium voltage-gated channel subfamily H member 3; potassium voltage-gated channel, subfamily H (eag-related), member 3; voltage-gated potassium channel subunit Kv12.2 Kcnh3|AU019351, C030044P22Rik, Elk, Elk2, Kv12.2, Melk, Melk2|potassium voltage-gated channel, subfamily H (eag-related), member 3|potassium voltage-gated channel subfamily H member 3|ELK channel 2|ether a go-go like|ether-a-go-go-like potassium channel 2|voltage-gated potassium channel subunit Kv12.2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Kcnh3, check out the Kcnh3 Infographic
![Kcnh3 infographic](/media/images/gene-infographic-example.jpg)
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Kcnh3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-KCNH3/Kv12.2 Antibody (A11947)
Hello CJ!
A11947 has been cited in 1 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
KCNH3 Predicts Poor Prognosis and Promotes Progression in Ovarian Cancer
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Customer Q&As
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5 Customer Q&As for Anti-KCNH3/Kv12.2 Antibody
Question
Will anti-KCNH3/Kv12.2 antibody A11947 work on monkey WB with right frontal lobe?
Verified Customer
Verified customer
Asked: 2020-03-04
Answer
Our lab technicians have not validated anti-KCNH3/Kv12.2 antibody A11947 on monkey. You can run a BLAST between monkey and the immunogen sequence of anti-KCNH3/Kv12.2 antibody A11947 to see if they may cross-react. If the sequence homology is close, then you can perform a pilot test. Keep in mind that since we have not validated monkey samples, this use of the antibody is not covered by our guarantee. However we have an innovator award program that if you test this antibody and show it works in monkey right frontal lobe in WB, you can get your next antibody for free.
Boster Scientific Support
Answered: 2020-03-04
Question
We are currently using anti-KCNH3/Kv12.2 antibody A11947 for rat tissue, and we are well pleased with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it likely that the antibody can work on bovine tissues as well?
Verified Customer
Verified customer
Asked: 2019-10-11
Answer
The anti-KCNH3/Kv12.2 antibody (A11947) has not been validated for cross reactivity specifically with bovine tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in bovine you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2019-10-11
Question
My question regards to test anti-KCNH3/Kv12.2 antibody A11947 on mouse brain for research purposes, then I may be interested in using anti-KCNH3/Kv12.2 antibody A11947 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?
Verified Customer
Verified customer
Asked: 2018-05-31
Answer
The products we sell, including anti-KCNH3/Kv12.2 antibody A11947, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.
Boster Scientific Support
Answered: 2018-05-31
Question
Will anti-KCNH3/Kv12.2 antibody A11947 work for WB with brain?
Verified Customer
Verified customer
Asked: 2018-02-09
Answer
According to the expression profile of brain, KCNH3 is highly expressed in brain. So, it is likely that anti-KCNH3/Kv12.2 antibody A11947 will work for WB with brain.
Boster Scientific Support
Answered: 2018-02-09
Question
I see that the anti-KCNH3/Kv12.2 antibody A11947 works with WB, what is the protocol used to produce the result images on the product page?
W. Wu
Verified customer
Asked: 2017-07-11
Answer
You can find protocols for WB on the "support/technical resources" section of our navigation menu. If you have any further questions, please send an email to [email protected]
Boster Scientific Support
Answered: 2017-07-11