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Product Info Summary
| SKU: | A03430 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-Kallikrein-4 KLK4 Antibody
View all Kallikrein 4/Prostase/EMSP1 Antibodies
SKU/Catalog Number
A03430
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Kallikrein-4 KLK4 Antibody (Catalog # A03430). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human.
Storage & Handling
KLK4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-Kallikrein-4 KLK4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03430)
Host
Rabbit
Contents
KLK4 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
KLK4 antibody was raised against a 15 amino acid peptide near the center of human KLK4. The immunogen is located within amino acids 80 - 130 of KLK4 .
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
KLK4 antibody is human specific. At least three isoforms of KLK4 are known to exist.
Reactive Species
A03430 is reactive to KLK4 in Human
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
27032 MW
Background of Kallikrein 4/Prostase/EMSP1
Kallikreins (KLKs) belong to the serine protease family of proteolytic enzymes having diverse physiological functions (1). Kallikrein 4 (KLK4), also known as prostase or EMSP1 (enamel matrix serine protease 1), contains one peptidase S1 domain and the expression in prostate is regulated by hormone (1,2). Many kallikreins are implicated in carcinogenesis and have potential as novel cancer and other disease biomarkers (3). KLK4 may have additional roles such as functioning as one of the two major enamel proteases identified that process enamel matrix proteins. Defects in KLK4 are the cause of amelogenesis imperfecta hypomaturation type 2A1 (AI2A1) (4).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A03430 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
KLK4 antibody can be used for detection of KLK4 by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of KLK4 in human kidney tissue lysate with KLK4 antibody at 1 μg/ml.
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Immunohistochemistry of KLK4 in human kidney tissue with KLK4 antibody at 5 μg/mL.
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Immunofluorescence of KLK4 in human kidney tissue with KLK4 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For KLK4 (Source: Uniprot.org, NCBI)
Gene Name
KLK4
Full Name
Kallikrein-4
Weight
27032 MW
Superfamily
peptidase S1 family
Alternative Names
ARM1, EMSP, PSTS, AI2A1, EMSP1, KLK-L1, PRSS17, kallikrein, Kallikrein-4, Enamel matrix serine proteinase 1 KLK4 AI2A1, ARM1, EMSP, EMSP1, KLK-L1, PRSS17, PSTS, kallikrein kallikrein related peptidase 4 kallikrein-4|androgen-regulated message 1|enamel matrix serine protease 1|enamel matrix serine proteinase 1|kallikrein-like protein 1|prostase|serine protease 17
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on KLK4, check out the KLK4 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for KLK4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Kallikrein-4 KLK4 Antibody (A03430)
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