Product Info Summary
SKU: | A06023 |
---|---|
Size: | 100 µl |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-ITPKB/Ip3Kb Antibody
SKU/Catalog Number
A06023
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-ITPKB/Ip3Kb Antibody (Catalog # A06023). Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-ITPKB/Ip3Kb Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06023)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from Internal of human ITPKB.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A06023 is reactive to ITPKB in Human, Mouse, Rat
Reconstitution
Restore with deionized water (or equivalent) for reconstitution volume of 100 µL
Calculated molecular weight
102376 MW
Background of ITPKB
The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity.
Dewaste V., Biochem. Biophys. Res. Commun. 291:400-405(2002).
Bertsch U., Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases.
Gregory S.G., Nature 441:315-321(2006).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A06023 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blotting: 1:500~1:3000
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of extracts from Jurkat cells, using ITPKB antibody A06023.
Protein Target Info & Infographic
Gene/Protein Information For ITPKB (Source: Uniprot.org, NCBI)
Gene Name
ITPKB
Full Name
Inositol-trisphosphate 3-kinase B
Weight
102376 MW
Superfamily
inositol phosphokinase (IPK) family
Alternative Names
Inositol-trisphosphate 3-kinase B;2.7.1.127;Inositol 1,4,5-trisphosphate 3-kinase B;IP3 3-kinase B;IP3K B;InsP 3-kinase B;ITPKB; ITPKB IP3-3KB, IP3K, IP3K-B, IP3KB, PIG37 inositol-trisphosphate 3-kinase B inositol-trisphosphate 3-kinase B|IP3 3-kinase B|IP3K B|inositol 1,4,5-trisphosphate 3-kinase B|insP 3-kinase B|proliferation-inducing protein 37
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ITPKB, check out the ITPKB Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ITPKB: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ITPKB/Ip3Kb Antibody (A06023)
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Customer Q&As
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3 Customer Q&As for Anti-ITPKB/Ip3Kb Antibody
Question
Is a blocking peptide available for product anti-ITPKB/Ip3Kb antibody (A06023)?
Verified Customer
Verified customer
Asked: 2019-09-17
Answer
We do provide the blocking peptide for product anti-ITPKB/Ip3Kb antibody (A06023). If you would like to place an order for it please contact [email protected] and make a special request.
Boster Scientific Support
Answered: 2019-09-17
Question
Is this A06023 anti-ITPKB/Ip3Kb antibody reactive to the isotypes of ITPKB?
K. Taylor
Verified customer
Asked: 2016-10-10
Answer
The immunogen of A06023 anti-ITPKB/Ip3Kb antibody is Synthesized peptide derived from Internal of human ITPKB. Could you tell me which isotype you are interested in so I can help see if the immunogen is part of this isotype?
Boster Scientific Support
Answered: 2016-10-10
Question
We are currently using anti-ITPKB/Ip3Kb antibody A06023 for rat tissue, and we are happy with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it possible that the antibody can work on feline tissues as well?
Z. Moore
Verified customer
Asked: 2015-01-20
Answer
The anti-ITPKB/Ip3Kb antibody (A06023) has not been tested for cross reactivity specifically with feline tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in feline you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2015-01-20