IL1RAPL1 Antibodies

AND IL1RAPL1 ELISA kits, IL1RAPL1 Proteins

Many biological assays use antibodies to detect IL1RAPL1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IL1RAPL1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IL1RAPL1 antibodies...

We validate the specificity of these antibodies to IL1RAPL1 by testing them on tissues known to express IL1RAPL1 positively and negatively. Browse below to find the IL1RAPL1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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IL1RAPL1 Infographic by Boster Bio

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Anti-IRPL1 IL1RAPL1 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A05104
100ul

IL1RAPL1 Overview

Facts about Interleukin-1 receptor accessory protein-like 1.

IL1RAPL1 3D structure. Source: alphafold

Interleukin-1 receptor accessory protein-like 1 (IL1RAPL1)

May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel (PubMed:12783849). May activate the MAP kinase JNK (PubMed:15123616).

Plays a role in neurite outgrowth (By similarity). During dendritic spine formation may bidirectionally induce pre- and post-synaptic differentiation of neurons by trans- synaptically binding to PTPRD (By similarity).

Gene Information

Human
Gene Name:	IL1RAPL1
Uniprot:	Q9NZN1
Entrez:	11141

Family

Belongs to:

interleukin-1 receptor family

Alternative Names

IL1R8IL1RAPL; IL-1R9; IL1RAPL1; IL-1RAPL1; IL-1-RAPL-1; IL-1RAPL-1; IL1RAPL-1; interleukin 1 receptor accessory protein-like 1; interleukin 1 receptor-8; interleukin-1 receptor accessory protein-like 1; mental retardation, X-linked 10; MRX10; MRX21; MRX34; oligophrenin-4; OPHN4mental retardation, X-linked 21; Three immunoglobulin domain-containing IL-1 receptor-related 2; TIGIRR-2; TIGIRR-2mental retardation, X-linked 34; X-linked interleukin-1 receptor accessory protein-like 1

Molecular Weight

Mass (kDA):
79.969 kDA

Genomic Context


Human

Location:	Xp21.3-p21.2
Sequence:	X; NC_000023.11 (28587446..29956718)

Tissue Specificity

Detected at low levels in heart, skeletal muscle, ovary, skin, amygdala, caudate nucleus, corpus callosum, hippocampus, substantia nigra and thalamus. Detected at very low levels in tonsil, prostate, testis, small intestine, placenta, colon and fetal liver.

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein. Cytoplasm. Cell projection, axon. Cell projection, dendrite. May localize to the cell body and growth cones of dendrite-like processes.

Diseases

Autistic Disorder
Impaired Cognition
Congenital Absence Of Adrenal Gland
Deficiency Of Glycerol Kinase
Hypoplasia
Autism Spectrum Disorders
Congenital Hypoplasia Of Adrenal Gland
Muscular Dystrophy, Duchenne
Malignant Neoplasms
Neoplasms
Dystrophy
Genetic Diseases, X-linked

Child Development Disorders, Pervasive
Muscular Dystrophy
Genomic Instability
Chromosome Inversion
Sex Chromosome Aberrations
Fragile X Syndrome

Pathways

Localization
Pathogenesis
Immune Response
Long-term Synaptic Potentiation
Cell Migration
Dna Methylation
Glycosylation
Inflammatory Response
Methylation
Phagocytosis

Cognition
Exocytosis
Autophagy
Secretion

PTMs

Phosphorylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IL1RAPL1

References

PMID: 10471494 by Carrie A., et al. A new member of the IL-1 receptor family highly expressed in hippocampus and involved in X-linked mental retardation.

PMID: 10757639 by Jin H., et al. Two novel members of the interleukin-1 receptor gene family, one deleted in Xp22.3-Xp21.3 mental retardation.