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Product Info Summary
| SKU: | PA2207-1 |
|---|---|
| Size: | 100 μg/vial |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-IRAKM/IRAK3 Antibody Picoband®
SKU/Catalog Number
PA2207-1
Size
100 μg/vial
Form
Lyophilized
Description
Boster Bio Anti-IRAKM/IRAK3 Antibody catalog # PA2207-1. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-IRAKM/IRAK3 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2207-1)
Host
Rabbit
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human IRAKM.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross-reactivity with other proteins
Reactive Species
PA2207-1 is reactive to IRAK3 in Human
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Observed Molecular Weight
53 kDa
Calculated molecular weight
67767 MW
Background of IRAK3
Interleukin-1 receptor-associated kinase 3, also called IRAK3 or IRAKM is an enzyme that in humans is encoded by the IRAK3 gene. The IRAKM gene consists of 12 exons spanning a region of approximately 60 kb in chromosome 12q14.3. This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
PA2207-1 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blot, 0.1-0.5μg/ml, Human
Positive Control
WB: HELA Cell, JURKAT Cell, HUT102 Cell,
Validation Images & Assay Conditions
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Anti-IRAKM antibody, PA2207-1, Western blotting
Lane 1: HELA Cell Lysate
Lane 2: JURKAT Cell Lysate
Lane 3: HUT102 Cell Lysate
Protein Target Info & Infographic
Gene/Protein Information For IRAK3 (Source: Uniprot.org, NCBI)
Gene Name
IRAK3
Full Name
Interleukin-1 receptor-associated kinase 3
Weight
67767 MW
Superfamily
protein kinase superfamily
Alternative Names
Interleukin-1 receptor-associated kinase 3;IRAK-3;2.7.11.1;IL-1 receptor-associated kinase M;IRAK-M;IRAK3 ; IRAK3 ASRT5, IRAKM interleukin 1 receptor associated kinase 3 interleukin-1 receptor-associated kinase 3|IL-1 receptor-associated kinase M
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on IRAK3, check out the IRAK3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for IRAK3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-IRAKM/IRAK3 Antibody Picoband® (PA2207-1)
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No publications found for PA2207-1
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