Product Info Summary
SKU: | A11126 |
---|---|
Size: | 100 µl |
Reactive Species: | Human, Mouse |
Host: | Rabbit |
Application: | IF, IHC, WB |
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Product info
Product Name
Anti-IPPK Antibody
SKU/Catalog Number
A11126
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-IPPK Antibody (Catalog # A11126). Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-IPPK Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A11126)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from internal of human IPPK.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A11126 is reactive to IPPK in Human, Mouse
Reconstitution
Calculated molecular weight
56017 MW
Background of IPPK
Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). InsP6 is involved in many processes such as mRNA export, non-homologous end-joining, endocytosis, ion channel regulation. It also protects cells from TNF-alpha-induced apoptosis.
Verbsky J.W., J. Biol. Chem. 277:31857-31862(2002).
Hulme D.J., Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases.
Ota T., Nat. Genet. 36:40-45(2004).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A11126 is guaranteed for IF, IHC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500
Validation Images & Assay Conditions
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Immunohistochemistry analysis of paraffin-embedded human brain tissue, using IPPK antibody A11126.
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Western blot analysis of extracts from RAW cells,K562 cells, LOVO cells and 3T3 cells, using IPPK antiobdy A11126.
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Immunofluorescence analysis of HepG2 cells, using IPPK antibody A11126.
Protein Target Info & Infographic
Gene/Protein Information For IPPK (Source: Uniprot.org, NCBI)
Gene Name
IPPK
Full Name
Inositol-pentakisphosphate 2-kinase
Weight
56017 MW
Superfamily
IPK1 type 2 family
Alternative Names
Inositol-pentakisphosphate 2-kinase;2.7.1.158;IPK1 homolog;Inositol-1,3,4,5,6-pentakisphosphate 2-kinase;Ins (1,3,4,5,6)P5 2-kinase;InsP5 2-kinase;IPPK;C9orf12; IPPK C9orf12, INSP5K2, IP5K, IPK1, bA476B13.1 inositol-pentakisphosphate 2-kinase inositol-pentakisphosphate 2-kinase|IPK1 homolog|inositol 1,3,4,5,6-pentakisphosphate 2-kinase|ins(1,3,4,5,6)P5 2-kinase|insP5 2-kinase
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on IPPK, check out the IPPK Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for IPPK: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-IPPK Antibody (A11126)
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No publications found for A11126
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Customer Q&As
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4 Customer Q&As for Anti-IPPK Antibody
Question
I have attached the WB image, lot number and protocol we used for erythroleukemia using anti-IPPK antibody A11126. Please let me know if you require anything else.
Verified Customer
Verified customer
Asked: 2019-07-25
Answer
Thank you very much for the data. Our lab team are working to resolve this as quickly as possible, and we appreciate your patience and understanding! You have provided everything we needed. Please let me know if there is anything you need in the meantime.
Boster Scientific Support
Answered: 2019-07-25
Question
Do you have a BSA free version of anti-IPPK antibody A11126 available?
S. Li
Verified customer
Asked: 2016-12-26
Answer
Thanks for your recent telephone inquiry. I can confirm that some lots of this anti-IPPK antibody A11126 are BSA free. For now, these lots are available and we can make a BSA free formula for you free of charge. It will take 3 extra days to prepare. If you require this antibody BSA free again in future, please do not hesitate to contact me and I will be pleased to check which lots we have in stock that are BSA free.
Boster Scientific Support
Answered: 2016-12-26
Question
Does anti-IPPK antibody A11126 work for IF with erythroleukemia?
M. Walker
Verified customer
Asked: 2015-12-24
Answer
According to the expression profile of erythroleukemia, IPPK is highly expressed in erythroleukemia. So, it is likely that anti-IPPK antibody A11126 will work for IF with erythroleukemia.
Boster Scientific Support
Answered: 2015-12-24
Question
Would anti-IPPK antibody A11126 work on monkey WB with esophagus mucosa?
D. Evans
Verified customer
Asked: 2013-11-14
Answer
Our lab technicians have not tested anti-IPPK antibody A11126 on monkey. You can run a BLAST between monkey and the immunogen sequence of anti-IPPK antibody A11126 to see if they may cross-react. If the sequence homology is close, then you can perform a pilot test. Keep in mind that since we have not validated monkey samples, this use of the antibody is not covered by our guarantee. However we have an innovator award program that if you test this antibody and show it works in monkey esophagus mucosa in WB, you can get your next antibody for free.
Boster Scientific Support
Answered: 2013-11-14