Click image to see more details
Product Info Summary
| SKU: | M11492 |
|---|---|
| Size: | 100 µg |
| Reactive Species: | Human, Mouse |
| Host: | Mouse |
| Application: | WB, FACS |
Customers Who Bought This Also Bought
Product info
Product Name
Anti-IL-17RE Antibody (Monoclonal, ABM2G70)
SKU/Catalog Number
M11492
Size
100 µg
Form
Liquid
Description
Boster Bio Anti-IL-17RE Antibody (Monoclonal, ABM2G70) (Catalog# M11492). Tested in FACS, WB application(s). This antibody reacts with Human, Mouse.
Storage & Handling
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Cite This Product
Anti-IL-17RE Antibody (Monoclonal, ABM2G70) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M11492)
Host
Mouse
Contents
100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide.
Clonality
Monoclonal
Clone Number
ABM2G70
Isotype
IgG2b Kappa
Immunogen
A partial length recombinant human IL-17RE protein (amino acids 50-268)
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Does not cross-react with primate, avian or amphibian GR.
Reactive Species
M11492 is reactive to IL17RE in Human, Mouse
Reconstitution
Reconstitute with distilled water.
Observed Molecular Weight
68 kDa
Calculated molecular weight
74810 MW
Background of IL-17RE
The regions of relatively constant sequence beyond the variable regions of immunoglobulins are termed constant regions (C regions) and are present in both the heavy and light chains. With very few exceptions, the sites of attachment for carbohydrates on immunoglobulins are located in these C regions. These regions also function to hold the variable regions together by using the disulfide bond between them. The C regions facilitate interaction with the antigen by increasing the maximum rotation of the immunoglobulin arms. Reportedly, a large population of patients with recurrent respiratory tract infection has low IgG4 concentrations. IgG4-related sclerosing disease has been recognized as a systemic disease entity characterized by an elevated serum IgG4 level, sclerosing fibrosis, and diffuse lymphoplasmacytic infiltration with the presence of many IgG4-positive plasma cells.IgG4 is overexpressed in inflammatory pseudotumor (IPT) and under expressed in inflammatory myofibroblastic tumor (IMT). In pulmonary nodular lymphoid hyperplasia (PNLH), there are an increased number of IgG4+ plasma cells.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M11492 is guaranteed for WB, FACS Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blot: 2-4 µg/ml
Flow cytometry: 2-4 µg/10^6 Cells
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of IL-17RE. Anti-IL-17RE antibody (Clone: ABM2G70) was tested at 2 μg/ml on (1) Jurkat, (2) PC3 and (3) NIH3T3 lysates.
Protein Target Info & Infographic
Gene/Protein Information For IL17RE (Source: Uniprot.org, NCBI)
Gene Name
IL17RE
Full Name
Interleukin-17 receptor E
Weight
74810 MW
Alternative Names
Interleukin-17 receptor E;IL-17 receptor E;IL-17RE;IL17RE;UNQ3056/PRO9877; Il17re|AA589509, IL-17RE, Il, Il25r|interleukin 17 receptor E|interleukin-17 receptor E|IL-17 receptor E
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on IL17RE, check out the IL17RE Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for IL17RE: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-IL-17RE Antibody (Monoclonal, ABM2G70) (M11492)
Hello CJ!
No publications found for M11492
*Do you have publications using this product? Share with us and receive a reward. Ask us for more details.
Recommended Resources
Here are featured tools and databases that you might find useful.
- Boster's Pathways Library
- Protein Databases
- Bioscience Research Protocol Resources
- Data Processing & Analysis Software
- Photo Editing Software
- Scientific Literature Resources
- Research Paper Management Tools
- Molecular Biology Software
- Primer Design Tools
- Bioinformatics Tools
- Phylogenetic Tree Analysis
Customer Reviews
Have you used Anti-IL-17RE Antibody (Monoclonal, ABM2G70)?
Submit a review and receive an Amazon gift card.
- $30 for a review with an image
0 Reviews For Anti-IL-17RE Antibody (Monoclonal, ABM2G70)
Customer Q&As
Have a question?
Find answers in Q&As, reviews.
Can't find your answer?
Submit your question
1 Customer Q&As for Anti-IL-17RE Antibody (Monoclonal, ABM2G70)
Question
We are currently using anti-IL-17RE antibody (Monoclonal, ABM2G70) M11492 for human tissue, and we are happy with the WB results. The species of reactivity given in the datasheet says human, mouse. Is it possible that the antibody can work on monkey tissues as well?
Verified Customer
Verified customer
Asked: 2017-06-28
Answer
The anti-IL-17RE antibody (Monoclonal, ABM2G70) (M11492) has not been validated for cross reactivity specifically with monkey tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in monkey you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2017-06-28
